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磁共振成像检测肝脏髓脂肪瘤:病例报告及文献综述。

MR imaging to detect myelolipomas of the liver: A case report and literature review.

作者信息

Xin Huizhen, Li Haijun, Yu Honghui, Zhang Juan, Peng Weizhi, Peng Dechang

机构信息

Department of Radiology, The First Affiliated Hospital, Nanchang University, Jiangxi Province, The People's Republic of China.

出版信息

Medicine (Baltimore). 2019 Jul;98(29):e16497. doi: 10.1097/MD.0000000000016497.

DOI:10.1097/MD.0000000000016497
PMID:31335715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6709097/
Abstract

RATIONALE

Primary hepatic myelolipoma is a rare benign neoplasm comprising mature adipose tissue and marrow components in various proportions. Chemical shift imaging (CSI) can distinguish the lipid within the tumor clearly; however, there have been no reports on the CSI of hepatic myelolipoma.

PATIENT CONCERN

A 20-year-old woman visited our hospital after discovering a space-occupying lesion in the liver with a history of more than 1 year. She felt distension pain and discomfort under the xiphoid process, accompanied by nausea, vomiting, and occasional chest oppression.

DIAGNOSIS

The tumor showed a well-defined mass with a pseudocapsule and a heterogeneous appearance on both T1- and T2-weighted magnetic resonance (MR) images. CSI analysis showed a signal decline within the tumor. Based on the histopathology, the tumor was diagnosed as hepatic myelolipoma.

INTERVENTIONS AND OUTCOMES

The patient underwent a right hepatectomy, and the postoperative vital signs were stable. Two weeks later, the patient was discharged safely.

LESSONS

Although hepatic myelolipoma is extremely rare, this condition should be considered in differential diagnosis when CSI shows that hepatic lesions contain fatty.

摘要

原理

原发性肝髓脂肪瘤是一种罕见的良性肿瘤,由不同比例的成熟脂肪组织和骨髓成分组成。化学位移成像(CSI)能够清晰地分辨肿瘤内的脂质;然而,目前尚无关于肝髓脂肪瘤化学位移成像的报道。

患者情况

一名20岁女性在发现肝脏占位性病变1年多后前来我院就诊。她感到剑突下胀痛不适,伴有恶心、呕吐,偶尔还有胸闷。

诊断

肿瘤在T1加权和T2加权磁共振(MR)图像上显示为边界清晰、有假包膜且外观不均匀的肿块。化学位移成像分析显示肿瘤内信号下降。根据组织病理学检查,该肿瘤被诊断为肝髓脂肪瘤。

干预措施及结果

患者接受了右肝切除术,术后生命体征平稳。两周后,患者安全出院。

经验教训

尽管肝髓脂肪瘤极为罕见,但当化学位移成像显示肝脏病变含有脂肪时,在鉴别诊断中应考虑到这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391b/6709097/eeacfc809fea/medi-98-e16497-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391b/6709097/9cb32e6d671e/medi-98-e16497-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391b/6709097/eeacfc809fea/medi-98-e16497-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391b/6709097/9cb32e6d671e/medi-98-e16497-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391b/6709097/eeacfc809fea/medi-98-e16497-g002.jpg

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本文引用的文献

1
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World J Gastroenterol. 2016 Nov 21;22(43):9654-9660. doi: 10.3748/wjg.v22.i43.9654.
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Adrenal myelolipoma: A rare lesion of adrenal gland.肾上腺髓质脂肪瘤:一种罕见的肾上腺病变。
Indian J Cancer. 2015 Oct-Dec;52(4):597-8. doi: 10.4103/0019-509X.178402.
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Contrast-enhanced ultrasound (CEUS) appearance of hepatic myelolipoma.肝脏髓脂肪瘤的超声造影(CEUS)表现。
磁共振成像及血清甲胎蛋白异质体L3和高尔基体蛋白73在原发性肝癌诊断中的应用
J Oncol. 2022 Mar 30;2022:1192368. doi: 10.1155/2022/1192368. eCollection 2022.
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Diagnostic imaging features of hepatic myelolipoma incarcerated in a peritoneopericardial diaphragmatic hernia in a cat.猫腹膜心包膈疝嵌顿肝髓脂肪瘤的诊断影像学特征。
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Unique case of metachronous adrenal and hepatic myelolipomas.肾上腺和肝同时发生的多发性骨髓脂肪瘤 1 例报告。
BMJ Case Rep. 2021 Mar 4;14(3):e240894. doi: 10.1136/bcr-2020-240894.
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Neoplastic and non-neoplastic proliferative disorders of the perirenal space: cross-sectional imaging findings.肾周间隙的肿瘤性和非肿瘤性增殖性疾病:横断面成像表现
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