采用超高效液相色谱-串联质谱法同时测定食品中的 20 种分散染料。
Simultaneous determination of 20 disperse dyes in foodstuffs by ultra high performance liquid chromatography-tandem mass spectrometry.
机构信息
College of Resources and Environment Science, Xinjiang University, Urumqi, China; Key Laboratory of Oasis Ecology, Ministry of Education, Xinjiang University, Urumqi, China.
Department of Technology, Xinjiang Entry-Exit Inspection and Quarantine Bureau, Urumqi, China.
出版信息
Food Chem. 2019 Dec 1;300:125183. doi: 10.1016/j.foodchem.2019.125183. Epub 2019 Jul 15.
A reasonable, high sensitive and accurate analytical method for the determination of 20 allergenic disperse dyes in foodstuffs was developed and validated. The obtained results showed that an ultra high liquid performance chromatography system - equipped with tandem quadrupole mass spectrometry (UHPLC-MS/MS) proved to be ideal for the selected method enabling multidimensional processing of the samples. Under optimized conditions, validation results showed excellent linearity (5-1000 µg/L, r ≥ 0.997), limits of detection (LODs, 1.1-10.8 μg/kg), recoveries (60.2-110.3%) and precision (RSDs ≤ 12.6%) for the twenty disperse dyes under investigation. The developed method was successfully applied to the analysis of 20 disperse dyes in real foodstuffs demonstrating the validity and applicability of the current method for continuing monitoring of the selected dyes. The proposed UHPLC-MS/MS is thus proved to be a convenient, effective, sensitive and timesaving method for the isolation and determination of allergenic disperse dyes in edible packaging and other foodstuffs.
建立并验证了一种用于检测食品中 20 种致敏分散染料的合理、高灵敏和准确的分析方法。所得结果表明，超高效液相色谱-串联四极杆质谱联用系统（UHPLC-MS/MS）非常适合所选方法，能够对样品进行多维处理。在优化条件下，验证结果表明该方法具有良好的线性（5-1000μg/L，r≥0.997）、检出限（LODs，1.1-10.8μg/kg）、回收率（60.2-110.3%）和精密度（RSDs≤12.6%）。该方法成功应用于实际食品中 20 种分散染料的分析，证明了该方法的有效性和适用性，可用于对选定染料的持续监测。因此，所提出的 UHPLC-MS/MS 是一种用于分离和测定食用包装材料和其他食品中致敏分散染料的便捷、有效、灵敏和省时的方法。
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