Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Medicina (Kaunas). 2019 Jul 11;55(7):364. doi: 10.3390/medicina55070364.
We present two cases demonstrating the nuances that must be considered when determining if a patient could benefit from low dose computed tomography (LDCT) lung cancer screening. Our case report discusses the available literature, where it exists, on lung cancer screening with special attention to the impact of chronic obstructive pulmonary disease (COPD), and poor functional status. Patients with COPD and concurrent smoking history are at higher risk of lung cancer and may therefore benefit from lung cancer screening. However, this population is at increased risk for complications related to biopsies and lobar resections. Appropriate interventions other than surgical resection exist for COPD patients with poor pulmonary reserve. Risks and benefits of lung cancer screening are unique to each patient and require shared decision-making.
我们呈现了两个案例,旨在展示在确定患者是否可以从低剂量计算机断层扫描 (LDCT) 肺癌筛查中获益时需要考虑的细微差别。我们的病例报告讨论了现有的肺癌筛查文献,特别关注慢性阻塞性肺疾病 (COPD) 和功能状态不佳的影响。患有 COPD 且有吸烟史的患者患肺癌的风险更高,因此可能受益于肺癌筛查。然而,该人群与活检和肺叶切除术相关的并发症风险增加。对于肺储备功能不佳的 COPD 患者,除了手术切除之外,还有其他适当的干预措施。肺癌筛查的风险和获益对每个患者都是独特的,需要进行共同决策。