Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA.
Departments of Obstetrics and Gynaecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
BMC Womens Health. 2019 Jul 23;19(1):102. doi: 10.1186/s12905-019-0797-z.
We tested whether childhood adversity is associated with poor cardiometabolic health in adulthood among a sample of overweight or obese Dutch women of reproductive age. Health behaviors, psychological distress, mood symptoms, or personality traits were included as potential mediators.
Data came from a follow-up visit (N = 115), carried out in 2016/2017, of a randomized controlled lifestyle intervention trial in 577 obese infertile women. The associations between total adversity exposure score and cardiometabolic health were tested with regression models. Sleep, smoking and eating behavior, symptoms of depression, anxiety and stress, and personality traits were potential mediators.
Childhood adversity scores were not associated with cardiometabolic outcomes but were associated with poorer sleep quality score (M = 7.2 (SD = 3.5) for those with ≥2 types of events versus 4.8 (2.9) for those with no events; p = 0.022), higher external eating score (26.4 (8.7) versus 21.8 (10.3); p = 0.038), higher perceived stress score (17.1 (6.8) versus 12.3 (4.5); p = 0.016), post-traumatic stress score (1.9 (1.5) versus 0.6 (1.1); p < 0.001), and lower agreeableness score (28.2 (4.2) versus 30.3 (3.1); p = 0.035).
Childhood adversity was associated with poorer health behaviors including sleep and eating behavior, and more stress-related symptoms, but not with women's cardiometabolic health.
我们测试了在荷兰超重或肥胖的育龄女性样本中，童年逆境是否与成年后较差的心血代谢健康有关。健康行为、心理困扰、情绪症状或人格特质被纳入潜在的中介因素。
数据来自一项随机对照生活方式干预试验的随访（n=115），于 2016/2017 年对 577 名肥胖不孕女性进行。使用回归模型检验总逆境暴露评分与心血代谢健康之间的关系。睡眠、吸烟和饮食行为、抑郁、焦虑和压力症状以及人格特质是潜在的中介因素。
童年逆境评分与心血代谢结果无关，但与睡眠质量评分较差相关（≥2 种事件者为 7.2（3.5），无事件者为 4.8（2.9）；p=0.022），外部进食评分较高（26.4（8.7）比 21.8（10.3）；p=0.038），感知压力评分较高（17.1（6.8）比 12.3（4.5）；p=0.016），创伤后应激评分较高（1.9（1.5）比 0.6（1.1）；p<0.001），以及宜人性评分较低（28.2（4.2）比 30.3（3.1）；p=0.035）。
童年逆境与较差的健康行为有关，包括睡眠和饮食行为，以及更多与压力相关的症状，但与女性的心血代谢健康无关。
