Department of Nutrition and Food Studies, Steinhart School of Culture, Education, and Human Development, New York University, New York, NY 10003, USA.
Nutrients. 2023 Dec 11;15(24):5069. doi: 10.3390/nu15245069.
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder experienced by women. PCOS is a lifelong condition associated with reproductive, metabolic, and psychological presentations. PCOS is also linked with increased prevalence of cardiometabolic risk factors. While an association between body weight and PCOS has been noted, cardiometabolic risk factors are prevalent in individuals with PCOS across body weights. Currently, no consensus exists as to the most appropriate lifestyle strategy for mitigating cardiometabolic risk in PCOS. A large proportion of the literature is focused on weight loss for individuals with PCOS who are overweight or experience obesity, despite PCOS being prevalent across body sizes. The aim of this narrative review is to assess dietary and lifestyle interventions aimed at reducing cardiometabolic risk in individuals with PCOS across body sizes. A total of 51 articles are included in this review. Overall, randomized controlled trials are limited and most studies focus on weight loss, excluding individuals classified within a healthy body weight range. Studies that modified the dietary pattern without an energy deficit saw improvements in cardiometabolic risk. Thus, less restrictive dietary approaches may be effective at reducing cardiometabolic risk in this population. This review also highlights the need for more sustainable lifestyle interventions that meet the needs of individuals with PCOS of varying body weights.
多囊卵巢综合征(PCOS)是女性最常见的内分泌紊乱疾病。PCOS 是一种与生殖、代谢和心理表现相关的终身疾病。PCOS 也与心血管代谢风险因素的患病率增加有关。虽然已经注意到体重与 PCOS 之间存在关联,但在不同体重的 PCOS 患者中,心血管代谢风险因素普遍存在。目前,对于减轻 PCOS 患者心血管代谢风险的最佳生活方式策略尚无共识。尽管 PCOS 存在于各种体型中,但大部分文献都集中在超重或肥胖的 PCOS 患者的体重减轻上。本叙述性综述的目的是评估针对不同体型的 PCOS 患者降低心血管代谢风险的饮食和生活方式干预措施。本综述共纳入 51 篇文章。总的来说,随机对照试验的数量有限,大多数研究都集中在体重减轻上,排除了体重正常范围内的个体。在不减少能量摄入的情况下改变饮食模式的研究发现,心血管代谢风险有所改善。因此,限制较少的饮食方法可能对该人群降低心血管代谢风险有效。本综述还强调了需要更可持续的生活方式干预措施,以满足不同体重的 PCOS 患者的需求。