Heo Min Jin, Kim Andre, Park Chan-Il
Institute of Marine Industry, College of Marine Science, Gyeongsang National University, 455, Tongyeong 650-160, Republic of Korea.
Department of Pharmaceutical Engineering, College of Medical and Life Science, Silla University, Busan 617-736, South Korea.
Data Brief. 2019 Apr 4;25:103901. doi: 10.1016/j.dib.2019.103901. eCollection 2019 Aug.
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Secretory carrier membrane protein 5 (SCAMP5) is expected to be involved in regulation of the immune response because it is expressed in a variety of immune tissues and promotes the secretion of cytokines in monocytes and macrophages. In this study, we performed an analysis of the molecular characteristics and phylogenetic of the SCAMP5 gene identified in (PmSCAMP5). In addition, we analysed PmSCAMP5 gene expression levels in the tissues of red sea bream infected with various pathogens [ (), () and Red sea bream iridovirus (RSIV)], and we analysed PmSCAMP5 gene expression levels in the tissues of healthy red sea bream. This study was carried out to provide basic data on the non-specific immune system of the red sea bream.
分泌载体膜蛋白（SCAMPs）是广泛分布的整合膜蛋白，与膜运输有关。分泌载体膜蛋白5（SCAMP5）有望参与免疫反应的调节，因为它在多种免疫组织中表达，并促进单核细胞和巨噬细胞中细胞因子的分泌。在本研究中，我们对在 [物种名称未给出] 中鉴定出的SCAMP5基因（PmSCAMP5）进行了分子特征和系统发育分析。此外，我们分析了感染各种病原体[ [病原体名称未给出]、[病原体名称未给出] 和红鳍东方鲀虹彩病毒（RSIV）]的红鳍东方鲀组织中PmSCAMP5基因的表达水平，并分析了健康红鳍东方鲀组织中PmSCAMP5基因的表达水平。开展本研究是为了提供有关红鳍东方鲀非特异性免疫系统的基础数据。
