Vokuhl C
Kindertumorregister der GPOH, Sektion Kinderpathologie, Institut für Pathologie, Universitätsklinikum SH, Campus Kiel, Arnold-Heller-Str. 10, Haus 4, 24105, Kiel, Deutschland.
Pathologe. 2019 Nov;40(6):600-608. doi: 10.1007/s00292-019-0638-8.
Pediatric kidney tumors are rare and account for about 6% of all childhood malignancies. By far the most common tumors are nephroblastomas. This review presents rare childhood renal tumors. Mesoblastic nephroma, as tumors of the low risk group, as well as the clear-cell sarcomas of the kidney and malignant rhabdoid tumors, as tumors of the high-risk group, and the so-called anaplastic sarcomas of the kidney will be discussed.Due to the significantly divergent therapy, a correct diagnosis is important. Due to the often overlapping morphology, pathologic diagnosis is often difficult. In addition to the typical morphologic features, the specific immunohistochemical aspects as well as the known molecular changes will be presented.
小儿肾肿瘤较为罕见，约占儿童所有恶性肿瘤的6%。迄今为止，最常见的肿瘤是肾母细胞瘤。本综述介绍了罕见的儿童肾肿瘤。将讨论低风险组的肿瘤——中胚叶肾瘤，以及高风险组的肿瘤——肾透明细胞肉瘤、恶性横纹肌样瘤，还有所谓的肾间变性肉瘤。由于治疗方法差异很大，正确诊断很重要。由于形态学特征常常重叠，病理诊断往往很困难。除了典型的形态学特征外，还将介绍特定的免疫组化方面以及已知的分子变化。
