Donikela Sangeetha, Mainkar Prathama S, Nayani Kiranmai, Chandrasekhar Srivari
Department of Organic Synthesis and Process Chemistry , CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.
Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110025 , India.
J Org Chem. 2019 Aug 16;84(16):10546-10553. doi: 10.1021/acs.joc.9b01660. Epub 2019 Aug 7.
A metal free DBU catalyzed synthesis of 1,2,3-triazole-fused dihydrobenzoxazinone derivatives by tandem β-azidation/[3 + 2] cycloaddition reaction has been developed under mild conditions. The methodological studies offer a broad scope and proceed well with a wide range of alkynylated cyclohexa 2,5-dienones, giving new -triazole-fused tricyclic scaffolds.
已开发出一种在温和条件下通过串联β-叠氮化/[3+2]环加成反应无金属DBU催化合成1,2,3-三唑稠合二氢苯并恶嗪酮衍生物的方法。方法学研究具有广泛的适用范围，能与多种炔基化的环己-2,5-二烯酮顺利反应，生成新的三唑稠合三环骨架。
