State Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering , Nanjing University , Nanjing 210093 , China.
Shenzhen Research Institute , Nanjing University , Shenzhen 518000 , China.
Org Lett. 2019 Aug 2;21(15):5884-5888. doi: 10.1021/acs.orglett.9b02016. Epub 2019 Jul 24.
A cobalt(III)-catalyzed, redox-neutral, intermolecular carboamination of propiolates and bicyclic alkenes was developed. This non-annulative coupling strategy features atom economy, high regioselectivity, good yields, and functional groups tolerance. Such a carboamination reaction was applied to modified phenols from the corresponding phenols under mild conditions.
发展了一种钴(III)催化、氧化还原中性、丙二酸盐和二环烯烃的分子间碳氨化反应。这种非稠合偶联策略具有原子经济性、高区域选择性、良好的收率和官能团耐受性。在温和条件下，该碳氨化反应可应用于相应酚类化合物的改性酚类化合物。
