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里约热内卢125例患者术后非典型分枝杆菌病

Post-surgical atypical mycobacteriosis in 125 patients in Rio de Janeiro.

作者信息

Pinheiro Patrícia Yvonne Maciel, Setúbal Sérgio, Oliveira Solange Artimos de

机构信息

Serviço de Infectologia, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Niterói, RJ, Brasil.

Disciplina de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal Fluminense, Niterói, RJ, Brasil.

出版信息

Rev Soc Bras Med Trop. 2019 Jul 18;52:e20190039. doi: 10.1590/0037-8682-0039-2019.

DOI:10.1590/0037-8682-0039-2019
PMID:31340363
Abstract

INTRODUCTION

The growing incidence of post-surgical atypical mycobacteriosis (PSAM) may be related to the increased use of low- and medium-complexity video-assisted surgery.

METHODS

Between April 2007 and June 2009, 125 patients were referred from the State Health Department of Rio de Janeiro for the treatment of confirmed, probable, or suspected PSAM.

RESULTS

Laparoscopic cholecystectomy was the most frequent surgical procedure (48.8%) among patients. Clarithromycin, ethambutol, and terizidone were used to treat 113 patients for a mean duration of 226 days.

CONCLUSIONS

Despite the need for multidrug therapy and long treatment duration, most included patients adhered to treatment and experienced cure without relapse.

摘要

引言

外科手术后非典型分枝杆菌病(PSAM)发病率的不断上升可能与低、中复杂度电视辅助手术的使用增加有关。

方法

2007年4月至2009年6月期间,125名患者从里约热内卢州卫生部转诊来接受确诊、疑似或可能的PSAM治疗。

结果

腹腔镜胆囊切除术是患者中最常见的外科手术(48.8%)。113名患者使用克拉霉素、乙胺丁醇和特立齐酮进行治疗,平均治疗时长为226天。

结论

尽管需要多药治疗且治疗时间长,但大多数纳入的患者坚持治疗并治愈且无复发。

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