Zhang Jiayuan, Cao Liu, Wang Yunxia, Jin Yuxia, Xiao Xiao, Zhang Qi
Chengdu University of Traditional Chinese Medicine, No. 37 Shierqiao Road, Jinniu District, Chengdu, Sichuan 610075, China.
Sichuan Integrative Medicine Hospital, South Renmin Road, Wuhou District, Chengdu, Sichuan 610041, China.
Evid Based Complement Alternat Med. 2019 Jun 25;2019:6246285. doi: 10.1155/2019/6246285. eCollection 2019.
Premenstrual syndrome (PMS) is one of the most common gynecological conditions with no standard modern therapeutic schedule. Some studies have reported the effects of acupuncture in treating PMS, but the intervention time varies. This review evaluated the efficacy of acupuncture for patients with PMS and the appropriate time to initiate acupuncture therapy. The review has been registered on the "PROSPERO" website; the registration number is CRD42018109724.
A comprehensive literature search was performed on 9 electronic databases from the time of inception to September 2018. RCTs studies on acupuncture for PMS compared with medication, sham acupuncture, or no treatment were included. Statistical analysis and investigation of heterogeneity source were carried out using RevMan5. 3.
A total of 15 studies, comprising of 1103 cases, were included. Overall, acupuncture significantly increased the effective rate of PMS compared with medicine and sham acupuncture. Subgroup analyses showed no significant difference among different intervention time to start acupuncture treatment. Among the acupoints involved in the treatment of PMS, SP6, LR3, and RN4 were the most commonly used.
The current meta-analysis reveals that acupuncture leads to better effective rate, but the intervention time has no significant effect on the efficacy of acupuncture treatment for PMS. SP6, LR3, and RN4 are the most commonly used acupoints in treating PMS. However, large-scale, case-control studies with rigorous designs are required to provide more accurate evidence.
经前综合征（PMS）是最常见的妇科疾病之一，目前尚无标准的现代治疗方案。一些研究报道了针刺治疗PMS的效果，但干预时间各不相同。本综述评估了针刺治疗PMS患者的疗效以及开始针刺治疗的合适时间。该综述已在“PROSPERO”网站注册，注册号为CRD42018109724。
对9个电子数据库从建库至2018年9月进行全面文献检索。纳入针刺治疗PMS与药物、假针刺或不治疗对比的随机对照试验（RCTs）研究。使用RevMan5.3进行统计分析和异质性来源调查。
共纳入15项研究，包括1103例病例。总体而言，与药物和假针刺相比，针刺显著提高了PMS的有效率。亚组分析显示，开始针刺治疗的不同干预时间之间无显著差异。在治疗PMS所涉及的穴位中，三阴交（SP6）、太冲（LR3）和关元（RN4）是最常用的。
当前的荟萃分析表明，针刺可获得更好的有效率，但干预时间对针刺治疗PMS的疗效无显著影响。三阴交（SP6）、太冲（LR3）和关元（RN4）是治疗PMS最常用的穴位。然而，需要大规模、设计严谨的病例对照研究来提供更准确的证据。
