Davila Pedro J, Ortiz-Rosario Jan C, Matinez Meliza, Toro Ana C, Echegaray Jose J, Correa-Rivas Maria, Oliver Armando L
Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USA.
Department of Endocrinology, University of Puerto Rico School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR, 00921, USA.
Am J Ophthalmol Case Rep. 2019 Jul 9;15:100511. doi: 10.1016/j.ajoc.2019.100511. eCollection 2019 Sep.
We report a rare case of a metastatic carcinoid tumor to the right lower lid masquerading as a chalazion.
A 78-year-old Hispanic woman who presented with a 3-month history of a non-resolving chalazion on the right lower lid despite aggressive medical treatment. The patient had a history of noninfectious anterior uveitis and primary hepatic carcinoid tumor that was incidentally diagnosed during the initial uveitis work-up. The right lower eyelid lesion was biopsied and histological and immunopathological analysis revealed a well differentiated neuroendocrine tumor consistent with a carcinoid tumor.
Neuroendocrine tumors should be considered as part of the differential diagnosis of focal, vascularized eyelid masses. To the authors best knowledge this is the first reported case of primary hepatic carcinoid tumor with metastasis to the eyelids. We also highlight the importance of pursuing a histopathologic diagnosis, in the setting of a non-resolving or recurrent chalazion.
我们报告一例罕见的转移性类癌肿瘤,伪装成睑板腺囊肿,累及右下眼睑。
一名78岁的西班牙裔女性,尽管接受了积极的药物治疗,但右下眼睑出现了一个持续3个月未消退的睑板腺囊肿。患者有非感染性前葡萄膜炎病史,在最初的葡萄膜炎检查中偶然诊断出原发性肝类癌肿瘤。对右下眼睑病变进行活检,组织学和免疫病理学分析显示为高分化神经内分泌肿瘤,与类癌肿瘤一致。
神经内分泌肿瘤应被视为局灶性、血管化眼睑肿物鉴别诊断的一部分。据作者所知,这是首例原发性肝类癌肿瘤转移至眼睑的报道病例。我们还强调了在睑板腺囊肿不消退或复发的情况下进行组织病理学诊断的重要性。