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意大利老年人群髋部骨折的发生率和费用:首次基于区域的评估。

Incidence and costs of hip fractures in elderly Italian population: first regional-based assessment.

机构信息

Euro Mediterranean Scientific Biomedical Institute, ISBEM Research Centre, via Reali di Bulgaria, 72023, Mesagne, Brindisi, Italy.

Department of Orthopaedics and Traumatology, University of Tor Vergata, Rome, Italy.

出版信息

Arch Osteoporos. 2019 Jul 24;14(1):81. doi: 10.1007/s11657-019-0619-9.

DOI:10.1007/s11657-019-0619-9
PMID:31342284
Abstract

UNLABELLED

We analyzed for the first-time hospitalizations and costs for hip fractures in the elderly Italian population at the regional level from 2007 to 2014. The number of fractures and the overall costs increased, mainly due to people aged > 85 in all the Italian regions, although at different rates.

OBJECTIVE

We aimed at evaluating the burden of hip fractures in elderly Italian population at the regional level.

METHODS

We analyzed national hospitalizations records 2007-2014 to compute standardized hospitalizations rates (SHR) due to hip fractures per 10,000 inhabitants at the regional level and average annual percent change (AAPC), along with related costs.

RESULTS

Hip fractures occurred in people over 65 years increased from 89,601 to 94,525 over 8 years. The overall increase in the number of hospitalizations is attributable only to people aged ≥85. Actually, in the 65-74 and 74-84 age groups, total hospitalizations decreased from 13,396 to 12,268 and from 40,733 to 37,786 respectively, while they increased from 35,472 to 44,471 in people aged ≥85 (women = 28,605 and men = 6,867 in 2007; women = 34,636 and men = 9,835 in 2014). Almost 50% of hip fractures were found to have been experienced by patients aged 85 or older in 2014 (with women ≥ 85 representing 36.6% of total fractures), in accordance with the higher prevalence of osteoporosis in this age group. Fractures increase in people aged ≥ 85 was two-folds higher in males (AAPC: + 5.0%; P > 0.05) than in females (AAPC: + 2.6%; P > 0.05). Increases in the number of hospitalizations and related costs were observed for all the regions, with the only exception of Lazio (AAPC: - 4.6%; P < 0.05) and Friuli Venezia Giulia (hip fractures AAPC: - 1.9%; P < 0.05). The most significant increases in hip fractures and related costs were recorded in Calabria (+ 2.7%), Campania (+ 2.2%), and Lombardia (+ 2.0%). At the national level, SHR per 10,000 inhabitants due to hip fractures decreased in all three examined age groups (65-74, 75-84, and ≥ 85), both in males and females during the 8-year period (P < 0.05). This reduction was confirmed also when looking at the regional dataset, with few exceptions concerning female population (AAPC not statistically significant). When looking at the SHR per 10,000 inhabitants for the entire nation, we recorded a decreasing trend also in females aged 85 years old and over but not in males ≥ 85. Actually, men aged ≥ 85 showed increased HR per 10,000 in 10 regions out of 20. Direct hospitalization and rehabilitation costs increased in all the regions over the 8-year period (although at different rates), except for Friuli Venezia Giulia (where costs decreased from 21 to 19 million Euros) and Lazio (from 107 to 87 million Euros). Lombardia and Piemonte were the regions spending the highest amount of money to treat hip fractures in elderly people (151 and 95 million Euros in the year 2014, respectively).

CONCLUSION

Hip fractures in the elderly population remain a major public health issue in all Italian regions, especially in people aged 85 years old and over, although the problem is starting to become more controlled compared with the past. Women represent the majority of hip fractures, but the highest increasing rate has been observed in men. Pilot projects at regional level targeting elderly people at higher risk of fractures and treatment compliance are needed.

摘要

目的

评估意大利各地区老年人群髋部骨折的负担。

方法

我们分析了 2007-2014 年国家住院记录,以计算每 10000 名居民髋部骨折的标准化住院率(SHR)和相关费用。

结果

65 岁以上人群髋部骨折从 89601 例增加到 94525 例,8 年内增加了 5.3%。总住院人数的增加仅归因于年龄≥85 岁的人群。实际上,在 65-74 岁和 74-84 岁年龄组中,总住院人数分别从 13396 例和 40733 例减少到 12268 例和 37786 例,而年龄≥85 岁的人群住院人数从 35472 例增加到 44471 例(女性分别为 28605 例和 6867 例;2007 年为 34636 例和 9935 例)。2014 年,髋部骨折患者中有近 50%年龄在 85 岁或以上(≥85 岁的女性占总骨折的 36.6%),与该年龄组骨质疏松症的高发率相符。85 岁及以上人群髋部骨折的发生率男性是女性的两倍(AAPC:+5.0%;P>0.05)。所有地区的住院人数和相关费用都有所增加,只有拉齐奥(AAPC:-4.6%;P<0.05)和弗留利-威尼斯朱利亚(AAPC:-1.9%;P<0.05)两个地区除外。卡拉布里亚(+2.7%)、坎帕尼亚(+2.2%)和伦巴第(+2.0%)的髋部骨折和相关费用增幅最大。在全国范围内,65-74 岁、75-84 岁和≥85 岁三个年龄组的每 10000 名居民髋部骨折 SHR 均有所下降(P<0.05)。在考虑到地区数据集时,这一趋势得到了证实,只有少数女性人口的情况除外(AAPC 无统计学意义)。当观察全国每 10000 名居民的 SHR 时,我们记录到 85 岁及以上女性的 SHR 呈下降趋势,但 85 岁及以上男性的 SHR 并未下降。实际上,≥85 岁的男性在 20 个地区中有 10 个地区的 SHR 呈上升趋势。所有地区的直接住院和康复费用在 8 年内都有所增加(尽管增长速度不同),除了弗留利-威尼斯朱利亚(费用从 2100 万欧元降至 1900 万欧元)和拉齐奥(从 1.07 亿降至 8700 万欧元)。伦巴第和皮埃蒙特是治疗老年髋部骨折花费最高的两个地区(分别为 2014 年 1.51 亿和 9500 万欧元)。

结论

意大利各地区老年人群髋部骨折仍然是一个主要的公共卫生问题,特别是在年龄≥85 岁的人群中,尽管与过去相比,这个问题开始得到更好的控制。女性占髋部骨折的大多数,但男性的增长率最高。需要在地区层面开展针对骨折风险较高的老年人群和治疗依从性的试点项目。

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