Department of Chemistry and International Institute of Nanotechnology , Northwestern University , 2145 Sheridan Road , Evanston , Illinois 60208 , United States.
U.S. Army Combat Capabilities Development Command Chemical Biological Center , 8198 Blackhawk Road , Aberdeen Proving Ground , Maryland 21010 , United States.
J Am Chem Soc. 2019 Aug 7;141(31):12229-12235. doi: 10.1021/jacs.9b06179. Epub 2019 Jul 25.
Zirconium-based metal-organic frameworks (Zr-MOFs) based on nets such as , , , , and with diverse potential applications have been widely reported. Zr-MOFs based on the highly connected 6,12-connected net, however, remain absent on account of synthetic challenges. Herein we report the ligand-directed reticular syntheses and isoreticular expansion of a series of Zr-MOFs with the edge-transitive net from 12-connected hexagonal-prismatic Zr nodes and 6-connected trigonal-prismatic linkers, i.e., microporous NU-1600, mesoporous NU-1601, and mesoporous NU-1602. These Zr-MOFs exhibit remarkable activities toward the destruction of a nerve agent (soman) and a nerve agent simulant (DMNP).
基于 、 、 、 和 等 网络的锆基金属有机骨架（Zr-MOFs）具有多种潜在应用，已被广泛报道。然而，基于高连接的 6,12-连接 网络的 Zr-MOFs 由于合成上的挑战而仍然缺失。在此，我们报告了一系列 Zr-MOFs 的配体导向的网状合成和等网扩展，这些 Zr-MOFs 具有由 12-连接的六方棱柱形 Zr 节点和 6-连接的三角棱柱形连接体组成的具有边传递性的 网络，即微孔 NU-1600、中孔 NU-1601 和中孔 NU-1602。这些 Zr-MOFs 对神经毒剂（沙林）和神经毒剂模拟物（DMNP）的破坏具有显著的活性。
