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揭开黑箱之谜:在一项多中心研究中探索抑郁症混合疗法的使用模式。

Unraveling the Black Box: Exploring Usage Patterns of a Blended Treatment for Depression in a Multicenter Study.

作者信息

Kemmeren Lise L, van Schaik Anneke, Smit Johannes H, Ruwaard Jeroen, Rocha Artur, Henriques Mário, Ebert David Daniel, Titzler Ingrid, Hazo Jean-Baptiste, Dorsey Maya, Zukowska Katarzyna, Riper Heleen

机构信息

Department of Research and Innovation, GGZ inGeest Specialized Mental Health Care, Amsterdam, Netherlands.

Psychiatry, Amsterdam Public Health Research Institute, Amsterdam Universitair Medische Centra, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

出版信息

JMIR Ment Health. 2019 Jul 25;6(7):e12707. doi: 10.2196/12707.

Abstract

BACKGROUND

Blended treatments, combining digital components with face-to-face (FTF) therapy, are starting to find their way into mental health care. Knowledge on how blended treatments should be set up is, however, still limited. To further explore and optimize blended treatment protocols, it is important to obtain a full picture of what actually happens during treatments when applied in routine mental health care.

OBJECTIVE

The aims of this study were to gain insight into the usage of the different components of a blended cognitive behavioral therapy (bCBT) for depression and reflect on actual engagement as compared with intended application, compare bCBT usage between primary and specialized care, and explore different usage patterns.

METHODS

Data used were collected from participants of the European Comparative Effectiveness Research on Internet-Based Depression Treatment project, a European multisite randomized controlled trial comparing bCBT with regular care for depression. Patients were recruited in primary and specialized routine mental health care settings between February 2015 and December 2017. Analyses were performed on the group of participants allocated to the bCBT condition who made use of the Moodbuster platform and for whom data from all blended components were available (n=200). Included patients were from Germany, Poland, the Netherlands, and France; 64.5% (129/200) were female and the average age was 42 years (range 18-74 years).

RESULTS

Overall, there was a large variability in the usage of the blended treatment. A clear distinction between care settings was observed, with longer treatment duration and more FTF sessions in specialized care and a more active and intensive usage of the Web-based component by the patients in primary care. Of the patients who started the bCBT, 89.5% (179/200) also continued with this treatment format. Treatment preference, educational level, and the number of comorbid disorders were associated with bCBT engagement.

CONCLUSIONS

Blended treatments can be applied to a group of patients being treated for depression in routine mental health care. Rather than striving for an optimal blend, a more personalized blended care approach seems to be the most suitable. The next step is to gain more insight into the clinical and cost-effectiveness of blended treatments and to further facilitate uptake in routine mental health care.

摘要

背景

将数字组件与面对面(FTF)治疗相结合的混合治疗方法,正开始在精神卫生保健领域得到应用。然而,关于如何设置混合治疗的知识仍然有限。为了进一步探索和优化混合治疗方案,全面了解在常规精神卫生保健中应用治疗时实际发生的情况非常重要。

目的

本研究的目的是深入了解用于治疗抑郁症的混合认知行为疗法(bCBT)不同组件的使用情况,并将实际参与情况与预期应用进行对比反思,比较初级保健和专科保健中bCBT的使用情况,并探索不同的使用模式。

方法

所使用的数据来自欧洲基于互联网的抑郁症治疗比较效果研究项目的参与者,这是一项欧洲多中心随机对照试验,比较bCBT与常规抑郁症护理。2015年2月至2017年12月期间,在初级和专科常规精神卫生保健机构招募患者。对分配到bCBT组且使用了Moodbuster平台且可获得所有混合组件数据的参与者群体进行分析(n = 200)。纳入的患者来自德国、波兰、荷兰和法国;64.5%(129/200)为女性,平均年龄为42岁(范围18 - 74岁)。

结果

总体而言,混合治疗的使用存在很大差异。观察到护理环境之间存在明显差异,专科保健中的治疗持续时间更长且面对面治疗次数更多,而初级保健中的患者对基于网络的组件使用更积极、更密集。开始接受bCBT治疗的患者中,89.5%(179/200)也继续采用这种治疗方式。治疗偏好、教育水平和共病疾病数量与bCBT参与情况相关。

结论

混合治疗可应用于常规精神卫生保健中接受抑郁症治疗的一组患者。与其追求最佳组合,更个性化的混合护理方法似乎最为合适。下一步是更深入地了解混合治疗的临床和成本效益,并进一步促进其在常规精神卫生保健中的应用。

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