Uecker Marie, Petersen Claus, Dingemann Carmen, Fortmann Caroline, Ure Benno M, Dingemann Jens
Center of Pediatric Surgery, Hannover Medical School and Bult Children's Hospital, Hannover, Germany.
Eur J Pediatr Surg. 2020 Feb;30(1):45-50. doi: 10.1055/s-0039-1693727. Epub 2019 Jul 25.
Management strategies for large omphaloceles remain controversial. In this study, we discuss the use of GRAVITAS (ational utoreposition utures), the method used at our institution when successful primary closure is deemed questionable. Patient's primary clinical course and long-term outcomes were analyzed.
This is a single-center retrospective analysis of all consecutive patients with omphaloceles treated between 1997 and 2018. Decision for GRAVITAS was made when the defect was estimated too large for primary closure. Traction sutures were placed in the fascia surrounding the defect and then suspended from the top of the incubator to allow gravitational autoreposition of the herniated organs. Ventilation and muscle relaxation were maintained until secondary closure, which was performed after the obtruding viscera had been reduced by repeated adjustment of the suture's tension. Data are presented as mean ± standard deviation.
Out of 49 patients with omphaloceles, 12 were treated with GRAVITAS, 33 underwent primary closure, and 4 were treated using Schuster's technique. Mean time to secondary closure after GRAVITAS was 7 ± 10 days. In nine of the patients who had isolated omphalocele, secondary closure was achieved after 4 ± 2 days. Ventilation time was 5 ± 2 days, and time to full feeds was 18 ± 16 days. In three patients (one with Fallot's tetralogy, one with Cantrell's pentalogy, and one with lung hypoplasia), abdominal closure was achieved after 17 ± 15 days. Due to cardiorespiratory comorbidity, ventilation time was >30 days. Five patients received initial closure of the skin and secondary fascial closure after 18 ± 15 months. One patient with prior fascial closure underwent later repair of an abdominal wall hernia. During follow-up (30 ± 35 months), one patient with gastrointestinal obstruction due to adhesions required laparotomy, and one patient with gastroesophageal reflux disease underwent fundoplication.
GRAVITAS is a feasible method for staged closure of large omphaloceles when successful primary closure is deemed questionable.
巨大脐膨出的管理策略仍存在争议。在本研究中,我们讨论了重力辅助自动复位法(GRAVITAS)的应用,这是我们机构在认为一期成功关闭有疑问时所采用的方法。分析了患者的主要临床病程和长期预后。
这是一项对1997年至2018年间所有连续性脐膨出患者进行的单中心回顾性分析。当估计缺损过大无法一期关闭时,决定采用重力辅助自动复位法。在缺损周围的筋膜上放置牵引缝线,然后从培养箱顶部悬吊,以使突出的器官通过重力自动复位。维持通气和肌肉松弛直至二期关闭,在通过反复调整缝线张力使突出的内脏回纳后进行二期关闭。数据以平均值±标准差表示。
在49例脐膨出患者中,12例采用重力辅助自动复位法治疗,33例接受一期关闭,4例采用舒斯特技术治疗。重力辅助自动复位法后二期关闭的平均时间为7±10天。在9例单纯脐膨出患者中,4±2天后实现二期关闭。通气时间为5±2天,完全喂养时间为18±16天。3例患者(1例法洛四联症、1例坎特雷尔五联症和1例肺发育不全)在17±15天后实现腹壁关闭。由于心肺合并症,通气时间>30天。5例患者在18±15个月后接受了皮肤一期关闭和二期筋膜关闭。1例先前接受筋膜关闭的患者后来接受了腹壁疝修补术。在随访期间(30±35个月),1例因粘连导致胃肠道梗阻的患者需要剖腹手术,1例胃食管反流病患者接受了胃底折叠术。
当一期成功关闭有疑问时,重力辅助自动复位法是一种可行的分期关闭巨大脐膨出的方法。