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脐膨出和腹裂患儿是否需要早期筋膜闭合?

Is early fascial closure necessary for omphalocele and gastroschisis?

作者信息

Krasna I H

机构信息

Division of Pediatric Surgery, UMDNJ-Robert Wood Johnson Medical School, New Brunswick 08903-0019.

出版信息

J Pediatr Surg. 1995 Jan;30(1):23-8. doi: 10.1016/0022-3468(95)90601-0.

Abstract

Before the introduction of the "silo" for gastroschisis, the main goal of surgery was to cover the defect with skin. Since the silo has been used, the goals have been (1) to cover the defect with SILASTIC sheets and return the extraabdominal contents to the abdominal cavity by progressive plication of the silo and (2) to eventually close the defect by fascia-to-fascia approximation, before 1 month of age. In many series, early definitive abdominal wall closure resulted in mortality rates of 10% to 30%, usually because of bowel necrosis and resulting sepsis. At the author's institution, 20 newborns with large omphaloceles or gastroschisis have been treated, and fascial closure was obtained by the second week in 10 infants. In ten babies it was impossible to obtain early fascial closure without tension, and these children were managed differently. A nonaggressive two-stage approach was used, in which the goals were (1) early return of contents to the abdominal cavity and (2) only skin and granulation coverage of the defect (without aiming for early fascial closure or partial fascial closure) with a small central SILASTIC patch. Stage 1 is reduction of abdominal contents to the abdomen, through plication of the silo, over a 9 to 14 day period. Stage 2 is removal of the silo and closure of the ventral abdominal wall defect using a SILASTIC patch to close most of the defect, after approximating fascia in the superior and inferior portions. If the skin cannot be closed, the patch usually separates in 14 to 21 days, the pellicle remaining becomes completely epithelialized in 1 to 2 months, and further surgery has not been necessary.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在采用“袋状法”治疗腹裂之前,手术的主要目标是用皮肤覆盖缺损。自从使用袋状法以来,目标变为:(1)用硅橡胶片覆盖缺损,并通过逐渐收紧袋状法将腹腔外的内容物回纳入腹腔;(2)在1月龄前最终通过筋膜对筋膜缝合来闭合缺损。在许多系列研究中,早期进行确定性腹壁闭合的死亡率为10%至30%,通常是由于肠坏死及由此导致的败血症。在作者所在的机构,20例患有巨大脐膨出或腹裂的新生儿接受了治疗,10例婴儿在第二周实现了筋膜闭合。另外10例婴儿无法在无张力的情况下早期进行筋膜闭合,对这些患儿采用了不同的处理方法。采用了一种非激进的两阶段方法,其目标是:(1)尽早将内容物回纳入腹腔;(2)仅用皮肤和肉芽组织覆盖缺损(不追求早期筋膜闭合或部分筋膜闭合),使用一小块中央硅橡胶片。第一阶段是在9至14天内通过收紧袋状法将腹腔内容物回纳入腹腔。第二阶段是在将近上下部分的筋膜后,移除袋状法并使用硅橡胶片闭合腹前壁缺损,以闭合大部分缺损。如果皮肤无法闭合,硅橡胶片通常在14至21天分离,残留的薄膜在1至2个月内完全上皮化,无需进一步手术。(摘要截选至250词)

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