Apostolopoulos Vasso
Institute for Health and Sport, Victoria University, Melbourne 3030, Australia.
Cancers (Basel). 2019 Jul 24;11(8):1041. doi: 10.3390/cancers11081041.
Designing cancer vaccines has been at the forefront of cancer research for over two-and-a-half decades. In particular, delivery methods used to stimulate effective and long-lasting immune responses have been the major focus. This special issue presents new tumor associated antigens, delivery methods, combination immune therapies, methods of measuring immunity induced following cancer vaccinations, and mechanisms in understanding tumor microenvironments and immunosuppression-all beneficial for the design of improved cancer vaccines.
二十多年来，癌症疫苗的设计一直处于癌症研究的前沿。特别是，用于激发有效且持久免疫反应的递送方法一直是主要焦点。本期特刊介绍了新的肿瘤相关抗原、递送方法、联合免疫疗法、测量癌症疫苗接种后诱导的免疫的方法，以及理解肿瘤微环境和免疫抑制的机制——所有这些都有利于设计改进的癌症疫苗。
