引产与产后出血。
Induction of labor and postpartum blood loss.
机构信息
Division of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
出版信息
BMC Pregnancy Childbirth. 2019 Jul 25;19(1):265. doi: 10.1186/s12884-019-2410-8.
BACKGROUND
To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor.
METHODS
In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin.
RESULTS
Rates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected.
CONCLUSIONS
Induction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage.
背景
分析与自发性分娩相比，引产对分娩后出血量的影响。
方法
本研究为产后出血前瞻性队列研究的二次分析，纳入 2015 年至 2016 年间的 965 例分娩，包括 380 例引产（39%）。主要结局参数为产后出血发生率、估计失血量和产后血红蛋白下降。
结果
引产组的产后出血和估计失血量与对照组无显著差异。引产组的血红蛋白下降量显著减少。多元线性回归分析表明，引产与血红蛋白下降减少相关。次要母婴结局不受影响。
结论
引产与产后出血量增加无关，不应被视为产后出血的危险因素。
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