Pediatric Rheumatology Unit, Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Borges Lagoa, 802 - Vila Clementino, São Paulo, 04038-001, Brazil.
Adv Rheumatol. 2019 Jul 25;59(1):32. doi: 10.1186/s42358-019-0078-4.
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects children and adolescents. Its prevalence varies greatly from one study to another according to the population and methodology. Some tools may be helpful in screening for suspected cases. The aim of this study is determine the prevalence of JIA in children and adolescent students in the city of São Paulo, Brazil.
This cross-sectional study was conducted from March 2016 to November 2017. It was based on a populational study envolving school children and adolescents from São Paulo, the largest city of Brazil. We randomly selected students under 16 years old from private schools with more than 1000 students who were evaluated through a specific questionnaire for screening suspected cases of chronic arthropathy (Early Diagnosis of Chronic Arthritis - 12 items - EDA-12) and subsequent anamnesis and rheumatologic physical examination for diagnostic confirmation.
We contacted all 79 schools in the universe, of which 12(15, 18%) agreed to participate in the study. A total of 21,119 questionnaires were handed out to the parents. We obtained a response of 5,710 (27%). In 108 cases the EDA-12 score was considered positive (≥ 5). We examined all these 108 "suspicious" children. In 10 cases, the rheumatologic evaluation confirmed the diagnosis of arthritis, since the subjects presented a history and physical examination compatible with JIA. The prevalence of JIA in children and adolescents was 0.196% (95% CI = 0.104-0.371%).
In this first Brazilian population study to evaluate the prevalence of JIA, we observed that the disease is relatively prevalent in our country (196 / 100.000 children), which is similar to that observed in other studies involving children from urban centers.
幼年特发性关节炎（JIA）是一种影响儿童和青少年的慢性炎症性疾病。根据人群和方法的不同，其患病率在不同的研究中差异很大。一些工具可能有助于筛选疑似病例。本研究旨在确定巴西圣保罗市儿童和青少年 JIA 的患病率。
这是一项横断面研究，于 2016 年 3 月至 2017 年 11 月进行。它基于一项涉及巴西最大城市圣保罗的儿童和青少年的人群研究。我们从拥有 1000 多名学生的私立学校中随机选择 16 岁以下的学生，通过专门的问卷评估疑似慢性关节炎（12 项早期关节炎诊断 - EDA-12）的病例，并进行病史和风湿病学体格检查以进行诊断确认。
我们联系了研究范围内的所有 79 所学校，其中 12 所（15.18%）同意参与研究。共向家长发放了 21119 份问卷，收到了 5710 份（27%）的回复。在 108 例中，EDA-12 评分被认为阳性（≥5）。我们检查了所有这 108 例“可疑”儿童。在 10 例中，风湿病学评估证实了关节炎的诊断，因为这些患者有符合 JIA 的病史和体格检查。儿童和青少年 JIA 的患病率为 0.196%（95%CI=0.104-0.371%）。
在这项评估 JIA 患病率的巴西首次人群研究中，我们发现该疾病在我国较为普遍（196/10 万儿童），与涉及城市中心儿童的其他研究相似。
