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饮食模式与中国绝经后妇女抑郁症状的关联。

Association of dietary patterns with depressive symptoms in Chinese postmenopausal women.

机构信息

Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin 300070, People's Republic of China.

Health Management Centre, Tianjin Medical University General Hospital, Tianjin 300070, People's Republic of China.

出版信息

Br J Nutr. 2019 Nov 28;122(10):1168-1174. doi: 10.1017/S0007114519001867. Epub 2019 Jul 26.

Abstract

Many components in diet have regulated oxidative stress, inflammatory reaction and even balance oestrogen levels. Because these factors are closely associated with depressive symptoms in postmenopausal women, it is considered that dietary factors are able to prevent and control depressive symptoms. On the other hand, a dietary pattern that considers the correlations and synergies between foods and nutrients is expected to have a greater impact on disease risk. The aim of the present study is to evaluate whether dietary patterns are associated with depressive symptoms in Chinese postmenopausal women. A cross-sectional study of 2051 postmenopausal women (mean age: 58·8 (sd 7·4) years) was conducted in Tianjin, China. Dietary consumption was assessed by a valid self-administered FFQ. Principal component analysis was used to derive three major dietary patterns: 'healthy', 'sweets' and 'traditional Tianjin' from eighty-eight food items. Depressive symptoms were assessed using the Zung Self-Rating Depression Scale, and cut-off point of 48 indicating serious depressive symptoms. The association between quartile of dietary patterns and depressive symptoms was assessed using multiple logistic regression analysis. The multivariable-adjusted OR of having depressive symptoms for increasing quartile of dietary patterns were as follows: healthy, 1·00, 0·79 (95 % CI 0·49, 1·28), 0·62 (95 % CI 0·37, 1·04) and 0·57 (95 % CI 0·33, 0·97); sweets, 1·00, 0·75 (95 % CI 0·42, 1·3), 1·08 (95 % CI 0·64, 1·81) and 1·66 (95 % CI 1·03, 2·71); and traditional Tianjin, 1·00, 1·02 (95 % CI 0·58, 1·79), 0·96 (95 % CI 0·54, 1·71) and 2·53 (95 % CI 1·58, 4·16), respectively. The present study demonstrated that a healthy dietary pattern was inversely associated with depressive symptoms. On the contrary, greater adherence to sweets and traditional Tianjin dietary patterns was associated with a higher prevalence of depressive symptoms.

摘要

许多饮食成分可调节氧化应激、炎症反应,甚至平衡雌激素水平。由于这些因素与绝经后妇女的抑郁症状密切相关,因此人们认为饮食因素可以预防和控制抑郁症状。另一方面,考虑食物和营养素之间的相关性和协同作用的饮食模式预计会对疾病风险产生更大的影响。本研究旨在评估饮食模式是否与中国绝经后妇女的抑郁症状有关。在中国天津进行了一项 2051 名绝经后妇女(平均年龄:58.8±7.4 岁)的横断面研究。通过有效的自我管理式 FFQ 评估饮食摄入情况。使用主成分分析从 88 种食物中得出三种主要的饮食模式:“健康”、“甜食”和“传统天津”。使用 Zung 自评抑郁量表评估抑郁症状,48 分表示严重抑郁症状。使用多元逻辑回归分析评估饮食模式四分位数与抑郁症状之间的关系。随着饮食模式四分位数的增加,出现抑郁症状的多变量调整 OR 如下:健康模式为 1.00、0.79(95%CI 0.49,1.28)、0.62(95%CI 0.37,1.04)和 0.57(95%CI 0.33,0.97);甜食模式为 1.00、0.75(95%CI 0.42,1.3)、1.08(95%CI 0.64,1.81)和 1.66(95%CI 1.03,2.71);传统天津模式为 1.00、1.02(95%CI 0.58,1.79)、0.96(95%CI 0.54,1.71)和 2.53(95%CI 1.58,4.16)。本研究表明,健康的饮食模式与抑郁症状呈负相关。相反,更多地遵循甜食和传统天津饮食模式与更高的抑郁症状患病率相关。

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