Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Jockey Club Institute of Ageing, The Chinese University of Hong Kong, Hong Kong, China.
Nutrients. 2021 Nov 29;13(12):4310. doi: 10.3390/nu13124310.
Extending healthspan is a major public health challenge. Diet is one of the modifiable factors for preventing age-related diseases and preserving overall good health status during aging. Optimizing individuals' intrinsic capacity, including domains in cognition, psychological, sensory function, vitality, and locomotion, has been proposed as a model of healthy aging by the World Health Organization. To better understand the relationships between a healthy diet and healthy aging, this review summarizes the recent epidemiologic and clinical data for dietary patterns that have been shown to play a role in (domains of) healthy aging. Regardless of priori or posteriori dietary patterns, it appears that dietary patterns centered on plant-based foods have a beneficial role in (domains of) healthy aging. Our review identified a knowledge gap in dietary patterns and multidimensional concepts of healthy aging. More epidemiological studies should consider intrinsic capacity as an outcome measure to further our understanding of a healthy diet and multidimensional concepts of healthy aging. When a sufficient number of epidemiological studies is available, evidence can be synthesized and clinical trials can be designed to evaluate a healthy diet as a strategy for healthy aging to further our progress in translating evidence to practice and promoting healthy aging.
延长健康寿命是一个主要的公共卫生挑战。饮食是预防与年龄相关的疾病和保持衰老过程中整体健康状态的可改变因素之一。世界卫生组织提出了一种健康老龄化模式,即优化个体的内在能力,包括认知、心理、感官功能、活力和运动等领域。为了更好地理解健康饮食与健康老龄化之间的关系,本综述总结了最近关于饮食模式的流行病学和临床数据,这些饮食模式被证明在(健康老龄化的)领域发挥作用。无论采用先验还是后验的饮食模式,以植物性食物为中心的饮食模式似乎对(健康老龄化的)领域有有益作用。我们的综述发现了饮食模式和多维健康老龄化概念之间的知识差距。更多的流行病学研究应将内在能力作为一个结果指标来考虑,以进一步了解健康饮食和多维健康老龄化概念。当有足够数量的流行病学研究可用时,可以综合证据并设计临床试验,以评估健康饮食作为健康老龄化的策略,从而推进将证据转化为实践和促进健康老龄化的进展。