Division of Neonatology, Case Western Reserve University, Rainbow Babies & Children's Hospital, Suite RBC 3100, Cleveland, OH 44106-6010, USA.
Case Western Reserve University, Rainbow Babies & Children's Hospital, 11100 Euclid Avenue, Suite RBC 3100, Cleveland, OH 44106-6010, USA.
Clin Perinatol. 2019 Sep;46(3):553-565. doi: 10.1016/j.clp.2019.05.006. Epub 2019 Jun 15.
Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship between IH and poor outcomes may depend on the patterns (frequency, duration, and timing) of the IH events. Current treatment modalities used in the clinical setting have been only partially successful in reducing the incidence of apnea and accompanying IH, but the risks and benefits of more aggressive interventions should include knowledge of the relationship between IH and morbidity.
间歇性低氧血症（IH）在新生儿早期很常见，尤其是早产儿。这些事件与多种疾病有关，包括早产儿视网膜病变、睡眠呼吸障碍、神经发育障碍和死亡率。IH 与不良结局之间的关系可能取决于 IH 事件的模式（频率、持续时间和时间）。目前临床应用的治疗方法仅部分成功地降低了呼吸暂停和伴随 IH 的发生率，但更积极干预的风险和益处应包括了解 IH 与发病率之间的关系。
