Mandala Vinod Kumar, Bollaboina Suresh Kumar Yadav, Changala Baburao, Kotha Rakesh, Kasula Lingareddy
Pediatrics, Kakatiya Medical College, Warangal, IND.
Pediatrics, Niloufer Hospital, Hyderabad, IND.
Cureus. 2023 Sep 19;15(9):e45561. doi: 10.7759/cureus.45561. eCollection 2023 Sep.
The goal of the present systematic review was to investigate the occurrence patterns of intermittent hypoxemia in newborns throughout the early postnatal period as well as the link between neonatal intermittent hypoxemia exposure and harmful consequences such as neonatal morbidity and death. We collected data from 2014 to 2023 using several abstracting, referencing, and indexing database libraries in the field of medical sciences. A total of 715 papers were evaluated by both authors, and only seven articles met the specified review criteria after a thorough analysis. In preterm neonates with intermittent hypoxia (IH), severe morbidities such as bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), motor impairment, and cognitive delay were found. Only one study that extended to 18 months noted mortality. The length and occurrence of intermittent hypoxemia and the stage of premature neonates at the time of delivery are all closely associated with these morbidities. Therefore, it becomes important to continuously measure the patterns of occurrence of intermittent hypoxemia during early postnatal life to avoid its long-term morbidity and mortality impact.
本系统评价的目的是调查新生儿在出生后早期间歇性低氧血症的发生模式，以及新生儿间歇性低氧血症暴露与新生儿发病率和死亡等有害后果之间的联系。我们在2014年至2023年期间，利用医学领域的多个文摘、参考文献和索引数据库收集数据。两位作者共评估了715篇论文，经过深入分析，只有7篇文章符合指定的评价标准。在患有间歇性缺氧（IH）的早产儿中，发现了诸如支气管肺发育不良（BPD）、早产儿视网膜病变（ROP）、运动障碍和认知延迟等严重疾病。只有一项追踪至18个月的研究记录了死亡率。间歇性低氧血症的时长和发生情况以及早产儿分娩时的阶段均与这些疾病密切相关。因此，持续监测出生后早期间歇性低氧血症的发生模式，以避免其对长期发病率和死亡率的影响，就显得尤为重要。
