Ribeiro Jaqueline-Lemes, Costa Fernanda-Herrera, Cavalcante Ana-Sueli-Rodrigues, Kaminagakura Estela, Carvalho Yasmin-Rodarte, Anbinder Ana-Lia
Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, São Paulo, Brazil.
J Clin Exp Dent. 2019 Jun 1;11(6):e582-e586. doi: 10.4317/jced.55684. eCollection 2019 Jun.
Vascular leiomyomas (VL) are benign lesions of perivascular origin. We report two new cases and discuss their clinical, histological and immunohistochemical characteristics, in order to facilitate the diagnosis and treatment of such lesions. The patients, both male, presented asymptomatic nodules located in the bottom of the labial sulcus and buccal mucosa. In the second case, color doppler ultrasonography was performed, which showed no change in blood flow. After excisional biopsies, a limited lesion was observed histologically, with multiple tortuous vessels of varying sizes and calibers, and among them, spindle cells bundles, positive for smooth muscle actin. Oral VLs have clinical features similar to those of other more common lesions, making preoperative diagnosis difficult. Imaging examination, such as color doppler ultrasonography, may help in diagnosis. In general, excisional biopsy is performed, due to the ease of removal of the lesion during surgery. The treatment of choice is the complete excision of the lesion, which has an excellent prognosis and a low rate of recurrence. Vascular leiomyoma, spindle cells, thrombus, Doppler.
血管平滑肌瘤（VL）是起源于血管周围的良性病变。我们报告两例新病例，并讨论其临床、组织学和免疫组化特征，以促进对此类病变的诊断和治疗。患者均为男性，表现为位于唇沟底部和颊黏膜的无症状结节。在第二例中，进行了彩色多普勒超声检查，结果显示血流无变化。切除活检后，组织学观察到一个局限性病变，有多个大小和口径各异的迂曲血管，其中有梭形细胞束，平滑肌肌动蛋白呈阳性。口腔VL的临床特征与其他更常见病变相似，术前诊断困难。彩色多普勒超声等影像学检查可能有助于诊断。一般来说，由于手术中病变易于切除，故进行切除活检。治疗的选择是彻底切除病变，其预后良好且复发率低。血管平滑肌瘤、梭形细胞、血栓、多普勒。
