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胃底折叠术失败后的挽救性手术:微创 Roux-en-Y 重建术。

Minimally invasive Roux-en-Y reconstruction as a salvage operation after failed nissen fundoplication.

机构信息

Department of General Surgery, Cleveland Clinic, Cleveland, OH, USA.

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.

出版信息

Surg Endosc. 2020 May;34(5):2211-2218. doi: 10.1007/s00464-019-07010-7. Epub 2019 Jul 25.

Abstract

BACKGROUND

Conversion of Nissen fundoplication to Roux-en-Y (RnY) anatomy may be indicated in patients with post-surgical complications or who fail to achieve durable control of their disease. Herein we describe the largest series of patients at a single institution who underwent minimally invasive conversion of Nissen fundoplication to RnY reconstruction.

METHODS

All patients with prior Nissen fundoplication which were converted to RnY anatomy at our institution from March 2009 through November 2017 were retrospectively reviewed and analyzed. Patients were identified based on CPT codes and the description of the operation performed. All cases with attempted minimally invasive approach were included for analysis.

RESULTS

Fifty patients underwent conversion from prior Nissen fundoplication to RnY anatomy during the study period. The cohort was 84.0% female with a mean age of 53.5 years and a median body mass index of 36.7 kg/m. Thirteen patients (26.0%) had multiple prior foregut operations. Complications from fundoplication that warranted revision included recurrent hiatal hernia (n = 16), post-surgical gastroparesis (n = 10), and mechanical complications from the wrap (n = 8). An additional fourteen patients underwent conversion to RnY for metabolic disease. The mean operative time and estimated blood loss were 266 min and 132 mL, respectively, with all but one (98.0%) completed with a minimally invasive approach. The median length of stay was 5 days. Complications included marginal ulcer (n = 2), superficial surgical site infection (n = 2), anastomotic leak (n = 2), and one case each of pulmonary embolism, small bowel obstruction, and gastrointestinal bleeding. There were no mortalities at a median follow-up of 12.4 months.

CONCLUSIONS

Conversion of prior Nissen fundoplication to RnY anatomy is technically challenging, although it is safe and feasible even in the setting of multiple prior foregut operations. A minimally invasive approach should be offered to patients by surgeons with experience in revisional foregut and bariatric surgery.

摘要

背景

对于术后并发症或疾病控制不佳的患者,可能需要将 Nissen 胃底折叠术转换为 Roux-en-Y(RnY)解剖结构。在此,我们描述了单中心最大系列的患者,他们接受了微创 Nissen 胃底折叠术转换为 RnY 重建术。

方法

对 2009 年 3 月至 2017 年 11 月期间在我院接受 Nissen 胃底折叠术转换为 RnY 解剖结构的所有患者进行回顾性分析。根据 CPT 代码和所行手术的描述来识别患者。所有尝试微创方法的病例均纳入分析。

结果

研究期间,有 50 例患者行 Nissen 胃底折叠术转换为 RnY 解剖结构。该队列的女性占 84.0%,平均年龄为 53.5 岁,中位数体重指数为 36.7kg/m。13 例患者(26.0%)有多次上消化道手术史。需要修正的胃底折叠术相关并发症包括复发性食管裂孔疝(n=16)、术后胃轻瘫(n=10)和包裹机械并发症(n=8)。另有 14 例患者因代谢疾病而行 RnY 转换。平均手术时间和估计失血量分别为 266 分钟和 132 毫升,除 1 例(98.0%)外,其余均采用微创方法完成。中位住院时间为 5 天。并发症包括边缘性溃疡(n=2)、浅表性手术部位感染(n=2)、吻合口漏(n=2)和各 1 例肺栓塞、小肠梗阻和胃肠道出血。中位随访 12.4 个月无死亡。

结论

将先前的 Nissen 胃底折叠术转换为 RnY 解剖结构具有一定的技术挑战性,但即使在多次上消化道手术的情况下,也是安全可行的。有经验的外科医生应向患者提供微创手术方法,包括再次进行上消化道手术和减重手术。

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