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[生物反馈对慢性下腰痛患者的疗效:对疼痛强度、心理因素和应激标志物的影响]

[Efficacy of biofeedback in patients with chronic low back pain : Impact on pain intensity, psychological factors and stress markers].

作者信息

Eichler J, Rachinger-Adam B, Kraft E, Azad S C

机构信息

Interdisziplinäre Schmerzambulanz und Tagesklinik Großhadern, Klinikum der Universität München, LMU München, Marchioninistr. 15, 81377, München, Deutschland.

Klinik für Anaesthesiologie, Klinikum der Universität München, LMU München, München, Deutschland.

出版信息

Schmerz. 2019 Dec;33(6):539-548. doi: 10.1007/s00482-019-0393-z.

Abstract

BACKGROUND

The treatment of patients with chronic pain should be carried out in interdisciplinary multimodal pain programs of which relaxation methods represent an integral part. The German disease management guidelines (NDGM) on nonspecific low back pain currently do not recommend biofeedback as a relaxation technique for chronic low back pain due to inadequate data. Furthermore, health insurances do not cover the costs of this treatment.

METHODS

The efficacy of a 2-week biofeedback treatment was evaluated in a study of 10 patients with chronic nonspecific low back pain and 10 healthy, age and gender-matched subjects. The parameters "well-being", "depressive mood" and "pain-related disability" were assessed based on three psychometric tests (KAB, ADS and PDI). The pain intensity was measured using a numeric rating scale (NRS) and biofeedback measurement parameters themselves as well as stress markers in blood (noradrenaline, cortisol and MMP-2) were also measured.

RESULTS

The relaxation response was demonstrated by the biofeedback-parameters. The treatment led to an improvement in well-being, depressive mood and pain-related disability. These results correlated with a reduction of noradrenaline and MMP-2 blood levels, whereas cortisol concentrations showed no change.

CONCLUSION

Biofeedback relaxation is a suitable method in the treatment of chronic non-specific low back pain. Its use in interdisciplinary multimodal pain programs should be encouraged.

摘要

背景

慢性疼痛患者的治疗应在跨学科多模式疼痛项目中进行,其中放松方法是不可或缺的一部分。德国关于非特异性腰痛的疾病管理指南(NDGM)目前因数据不足,不推荐将生物反馈作为慢性腰痛的一种放松技术。此外,医疗保险不涵盖这种治疗的费用。

方法

在一项研究中,对10例慢性非特异性腰痛患者和10名年龄、性别匹配的健康受试者进行了为期2周的生物反馈治疗效果评估。基于三项心理测量测试(KAB、ADS和PDI)评估“幸福感”“抑郁情绪”和“疼痛相关残疾”等参数。使用数字评分量表(NRS)测量疼痛强度,还测量了生物反馈测量参数本身以及血液中的应激标志物(去甲肾上腺素、皮质醇和MMP-2)。

结果

生物反馈参数显示出放松反应。该治疗使幸福感、抑郁情绪和疼痛相关残疾得到改善。这些结果与去甲肾上腺素和血液中MMP-2水平的降低相关,而皮质醇浓度没有变化。

结论

生物反馈放松是治疗慢性非特异性腰痛的一种合适方法。应鼓励在跨学科多模式疼痛项目中使用。

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