慢性下腰痛治疗新方法与药物制剂分析
An Analysis of New Approaches and Drug Formulations for Treatment of Chronic Low Back Pain.
作者信息
Bhangare Karishma Patel, Kaye Alan D, Knezevic Nebojsa Nick, Candido Kenneth D, Urman Richard D
机构信息
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Department of Anesthesiology and Pain Medicine, Louisiana State University School of Medicine, LSU Health Science Center, 1542 Tulane Avenue, Room 659, New Orleans, LA 70112, USA.
出版信息
Anesthesiol Clin. 2017 Jun;35(2):341-350. doi: 10.1016/j.anclin.2017.01.023. Epub 2017 Mar 14.
The prevalence of chronic low back pain (CLBP) is increasing. Treatment is effective in less than 50% of patients after 1 year. This review investigates new treatments for CLBP. An extensive literature review focuses on new treatments for CLBP. Their safety and efficacy were evaluated and are described in detail in this review. The investigation identified new treatments for CLBP including chemonucleolysis, platelet-rich plasma injections, artemin, tanezumab, and stem cells. Further research and innovation are needed to implement these methods into practice and assess clinical significance. The current evidence suggests that there are promising new agents for the treatment of CLBP.
慢性下腰痛（CLBP）的患病率正在上升。一年后，不到50%的患者治疗有效。本综述调查CLBP的新治疗方法。广泛的文献综述聚焦于CLBP的新治疗方法。对其安全性和有效性进行了评估，并在本综述中详细描述。该调查确定了CLBP的新治疗方法，包括化学髓核溶解术、富血小板血浆注射、Artemin、他尼珠单抗和干细胞。需要进一步的研究和创新，以将这些方法应用于实践并评估其临床意义。目前的证据表明，有前景良好的新药物可用于治疗CLBP。
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