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我们能得到什么?通过对有旅行史的献血者进行额外检测来增加血液供应。

Who do we gain? Enhancement of blood supplies by additional testing for donors who travel.

作者信息

Reynolds C A, Cieply L, Sell J, Brailsford S R

机构信息

NHS Blood and Transplant/Public Health England Epidemiology Unit, NHS Blood and Transplant, London, UK.

NHS Blood and Transplant, Bristol, UK.

出版信息

Transfus Med. 2019 Oct;29(5):325-331. doi: 10.1111/tme.12620. Epub 2019 Jul 25.

Abstract

AIMS/OBJECTIVES: To describe the impact of additional testing on the England blood supply.

BACKGROUND

The blood service for England, NHS Blood and Transplant, applies a system of deferral and testing to donors with potential exposure to Chagas disease, malaria and West Nile virus; however, testing costs must be justified. Here, we describe the donations and donors gained by testing.

METHODS

Donation testing results and demographic data on donors in England where additional testing was applied were analysed in 2012-2016. The total number and proportion of donations tested, reactive and confirmed positive were calculated. Proportions of donors requiring additional tests were calculated by ethnic group for first-time and repeat donors.

RESULTS

Additional testing for travel was applied to 3·5% of NHSBT blood donations between 2012 and 2016. Over 98% of these tests were non-reactive. Only malaria tests were confirmed positive, in 1·7% of donations tested. In first-time donors, 45 and 40% of Asian and Black donors required an additional test, respectively, mainly for malaria. Testing for West Nile virus increased from 1·5% in 2012 to 2·2% of donations in 2016.

CONCLUSION

The majority of additional tests were screened negative, allowing approximately 64 000 donations to be released for issue annually. Donors most affected by malaria testing were more likely to have rare blood groups and be targeted for recruitment, whereas those given West Nile virus testing were mainly regular donors required for continuity of supply. These data show differences in the characteristics of donors by test and can be used to inform decisions about additional testing and deferrals.

摘要

目的

描述额外检测对英格兰血液供应的影响。

背景

英格兰的血液服务机构,即国民保健服务血液与移植中心,对可能接触恰加斯病、疟疾和西尼罗河病毒的献血者采用延期献血和检测系统;然而,检测成本必须合理。在此,我们描述通过检测获得的献血量和献血者情况。

方法

对2012 - 2016年英格兰进行额外检测的献血者的检测结果和人口统计学数据进行分析。计算检测的献血总量、呈反应性和确诊为阳性的比例。按种族计算首次献血者和重复献血者中需要额外检测的献血者比例。

结果

2012年至2016年期间,3.5%的国民保健服务血液与移植中心的献血进行了旅行相关的额外检测。其中超过98%的检测结果为非反应性。仅疟疾检测确诊为阳性,占检测献血量的1.7%。在首次献血者中,分别有45%的亚洲献血者和40%的黑人献血者需要额外检测,主要是针对疟疾。西尼罗河病毒检测从2012年的1.5%增加到2016年的2.2%。

结论

大多数额外检测结果为阴性,每年约有64000份血液可放行用于发放。受疟疾检测影响最大的献血者更有可能拥有稀有血型且是招募对象,而接受西尼罗河病毒检测的主要是为保证血液供应连续性所需的定期献血者。这些数据显示了不同检测项目下献血者特征的差异,可用于为额外检测和延期献血的决策提供参考。

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