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使用非培养的再生上皮悬液改善皮肤颜色和瘢痕:8例报告及文献复习

The use of noncultured regenerative epithelial suspension for improving skin color and scars: A report of 8 cases and review of the literature.

作者信息

Ren Jie, Liu Jianlan, Yu Nanze, Zhang Wenchao, Qian Hui, Liu Zhifei, Zhu Ningwen

机构信息

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

Department of Plastic Surgery, Peking Union Medical Hospital, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

J Cosmet Dermatol. 2019 Oct;18(5):1487-1494. doi: 10.1111/jocd.13071. Epub 2019 Jul 26.

DOI:10.1111/jocd.13071
PMID:31347758
Abstract

BACKGROUND

Regenerative Epithelial Suspension can lead to the restoration of wound and repigmentation, which can be gained by ReCell medical device to treat scar and depigmentation diseases.

OBJECTIVES

To report the effectivity of ReCell combined with microdermabrasion in scar and depigmentation diseases and review the literature of this new technology.

METHODS

We gave a differential donor⁄recipient ratio of about 1:20-30 with vitiligo, 1:40 with postburn construction, 1:80 with acne scar, and 1:120 with adult congenital melanocytic nevus, 1:80 with pediatrics, respectively. Photographs of patients before treatment and 3 months following the last treatment session were used to evaluate the effectivity.

RESULTS

A total of 8 patients including vitiligo vulgaris, postburn reconstruction, acne scars, and congenital melanocytic nevi treated by ReCell technology combined with microdermabrasion showed significant improvement in skin texture and color. And 17 studies of the research on ReCell technology were totally included in the systematic review.

CONCLUSION

Our investigation showed that Regenerative Epithelial Suspension gained by ReCell technology combined with microdermabrasion may improve scar and depigmentation diseases.

摘要

背景

再生上皮悬浮液可促进伤口愈合和色素沉着恢复,可通过ReCell医疗器械治疗瘢痕和色素脱失性疾病。

目的

报告ReCell联合微晶磨皮术治疗瘢痕和色素脱失性疾病的有效性,并综述该新技术的相关文献。

方法

对于白癜风患者,供体与受体比例约为1:20 - 30;烧伤后整形患者为1:40;痤疮瘢痕患者为1:80;成人先天性黑素细胞痣患者为1:120,儿科患者为1:80。使用患者治疗前及最后一次治疗后3个月的照片评估疗效。

结果

8例接受ReCell技术联合微晶磨皮术治疗的患者,包括寻常型白癜风、烧伤后整形、痤疮瘢痕和先天性黑素细胞痣,皮肤质地和颜色均有显著改善。系统评价共纳入17项关于ReCell技术的研究。

结论

我们的研究表明,ReCell技术联合微晶磨皮术获得的再生上皮悬浮液可能改善瘢痕和色素脱失性疾病。

相似文献

1
The use of noncultured regenerative epithelial suspension for improving skin color and scars: A report of 8 cases and review of the literature.使用非培养的再生上皮悬液改善皮肤颜色和瘢痕:8例报告及文献复习
J Cosmet Dermatol. 2019 Oct;18(5):1487-1494. doi: 10.1111/jocd.13071. Epub 2019 Jul 26.
2
[A novel treatment for facial acne scars: dermabrasion combined with Recell® (skin active cell transplantation) technique].一种治疗面部痤疮瘢痕的新方法:磨皮术联合Recell®(皮肤活性细胞移植)技术
Zhonghua Zheng Xing Wai Ke Za Zhi. 2014 Nov;30(6):417-20.
3
The Clinical Efficacy of ReCell® Autologous Cell Regeneration Techniques Combined with Dermabrasion Treatment in Acne Scars.Recell® 自体细胞再生技术联合磨皮术治疗痤疮瘢痕的临床疗效。
Aesthetic Plast Surg. 2020 Apr;44(2):535-542. doi: 10.1007/s00266-019-01481-8. Epub 2019 Aug 26.
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ReCell Spray-On Skin System for Treating Skin Loss, Scarring and Depigmentation after Burn Injury: A NICE Medical Technology Guidance.ReCell 喷雾式皮肤再生系统治疗烧伤后皮肤缺失、瘢痕和色素脱失:NICE 医疗技术指导
Appl Health Econ Health Policy. 2019 Apr;17(2):131-141. doi: 10.1007/s40258-018-00457-0.
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A single institution case series of ReCell use in treating pediatric burns.关于ReCell用于治疗小儿烧伤的单机构病例系列研究。
Int J Burns Trauma. 2023 Apr 15;13(2):78-88. eCollection 2023.
6
Treatment of stable vitiligo hands by ReCell system: a preliminary report.ReCell 系统治疗手部稳定型白癜风:初步报告。
Eur Rev Med Pharmacol Sci. 2010 Aug;14(8):691-4.
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Treatment of stable vitiligo by ReCell system.使用ReCell系统治疗稳定期白癜风。
Acta Dermatovenerol Croat. 2009;17(4):273-8.
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Follicular Unit "Exploitation": Follicular Unit Extraction Followed by Laser Hair Reduction-A Novel Approach to Repigmentation of Postburn Leukodermic Scars.毛囊单位“利用”:毛囊单位提取联合激光脱毛——一种治疗烧伤后白色瘢痕色素再生的新方法。
J Cutan Aesthet Surg. 2019 Jul-Sep;12(3):179-182. doi: 10.4103/JCAS.JCAS_61_19.
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Effect of Dermabrasion and ReCell on Large Superficial Facial Scars Caused by Burn, Trauma and Acnes.磨皮术和ReCell对烧伤、创伤和痤疮所致面部大面积浅表瘢痕的影响。
Chin Med Sci J. 2016 Sep 20;31(3):173-179. doi: 10.1016/s1001-9294(16)30047-5.
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Treatment of vitiligo lesions by ReCell vs. conventional melanocyte-keratinocyte transplantation: a pilot study.ReCell 与传统黑素细胞-角质形成细胞移植治疗白癜风皮损的一项初步研究。
Br J Dermatol. 2008 Jan;158(1):45-9. doi: 10.1111/j.1365-2133.2007.08216.x. Epub 2007 Oct 10.

引用本文的文献

1
ReCell Combined With NB-UVB for the Treatment of Extensive Stable Vitiligo: A Randomized Controlled Trial.ReCell联合窄谱中波紫外线治疗大面积稳定期白癜风:一项随机对照试验
J Cosmet Dermatol. 2025 Feb;24(2):e70032. doi: 10.1111/jocd.70032.
2
Top Skin-of-Color Publications in Dermatology.皮肤科领域关于有色人种皮肤的顶级出版物。
JMIR Dermatol. 2022 Jun 6;5(2):e37256. doi: 10.2196/37256.
3
Burn injury.烧伤
Nat Rev Dis Primers. 2020 Feb 13;6(1):11. doi: 10.1038/s41572-020-0145-5.