Hefei National Laboratory for Physical Sciences at the Microscale, Key Laboratory of Surface and Interface Chemistry and Energy Catalysis of Anhui Higher Education Institutes, Department of Chemical Physics , University of Science and Technology of China , Hefei 230026 , P. R. China.
Faculty of Materials Science and Engineering , South China University of Technology , 510640 Guangzhou , P. R. China.
Langmuir. 2019 Aug 27;35(34):11157-11166. doi: 10.1021/acs.langmuir.9b01740. Epub 2019 Aug 13.
It is expected that the widely dispersed ions in seawater would have strong influence on the performance of polymeric marine antibiofouling materials through the modulation of enzymatic degradation of the materials. In this work, poly(ε-caprolactone)-based polyurethane and poly(triisopropylsilyl methacrylate--2-methylene-1,3-dioxepane) have been employed as model systems to explore the specific ion effects on the enzymatic degradation of polymeric marine antibiofouling materials. Our study demonstrates that the specific ion effects on the enzymatic degradation of the polymer films are closely correlated with the ion-specific enzymatic hydrolysis of the ester. In the presence of different cations, the effectiveness of the enzyme to degrade the polymer films is dominated by the direct specific interactions between the cations and the negatively charged enzyme molecules. In the presence of different anions, the kosmotropic anions give rise to a high enzyme activity in the degradation of polymer films induced by the salting-out effect, whereas the chaotropic anions lead to a low enzyme activity in the degradation of the polymer films owing to the salting-in effect. This work highlights the opportunities available for the use of specific ion effects to modulate the enzymatic degradation of polymeric antibiofouling materials in the marine environment.
预计海水中广泛分散的离子会通过调节材料的酶降解来对聚合物海洋防污材料的性能产生强烈影响。在这项工作中，聚（己内酯）基聚氨酯和聚（三异丙基硅基甲基丙烯酸酯-2-亚甲基-1,3-二恶烷）已被用作模型系统，以探索特定离子对聚合物海洋防污材料的酶降解的影响。我们的研究表明，特定离子对聚合物薄膜的酶降解的影响与酯的特定离子酶水解密切相关。在存在不同阳离子的情况下，酶降解聚合物薄膜的有效性受阳离子与带负电荷的酶分子之间的直接特定相互作用支配。在存在不同阴离子的情况下，亲水性阴离子由于盐析效应导致聚合物薄膜降解过程中酶活性高，而疏水性阴离子由于盐溶效应导致聚合物薄膜降解过程中酶活性低。这项工作强调了利用特定离子效应来调节聚合物防污材料在海洋环境中的酶降解的机会。
