From the Department of Nuclear Medicine, Prince of Wales Hospital, Randwick.
Faculty of Medicine, University of New South Wales, Sydney.
Clin Nucl Med. 2019 Oct;44(10):797-798. doi: 10.1097/RLU.0000000000002727.
We report a case of a 75-year-old man with concomitant metastatic prostate cancer and progressive follicular lymphoma and the utility of molecular imaging in differentiating these 2 conditions. F-FDG PET/CT can offer accurate staging in many cancers, although its role in prostate cancer is limited. The role of F-DCFPyL (PSMA) PET/CT in prostate cancer is evolving and has been demonstrated to have a higher sensitivity than conventional bone scan and CT scan. Together, FDG and PSMA PET/CT studies may offer a noninvasive approach to individually characterize concomitant malignancies, aiding optimization of management and follow-up.
我们报告了一例 75 岁男性，同时患有转移性前列腺癌和进行性滤泡性淋巴瘤，并探讨了分子成像在区分这两种疾病中的作用。18F-FDG PET/CT 可在许多癌症中提供准确的分期，尽管在前列腺癌中的作用有限。18F-DCFPyL（PSMA）PET/CT 在前列腺癌中的作用正在不断发展，其敏感性已被证明高于传统的骨扫描和 CT 扫描。FDG 和 PSMA PET/CT 研究一起可能提供一种非侵入性的方法来单独描述同时存在的恶性肿瘤，有助于优化管理和随访。
