From the Department of Urology, Amsterdam University Medical Centers, Location VU Medical Center, Amsterdam.
Department of Nuclear Medicine, Noordwest Ziekenhuisgroep, Location Alkmaar, Alkmaar, the Netherlands.
Clin Nucl Med. 2020 Feb;45(2):e96-e97. doi: 10.1097/RLU.0000000000002738.
A 75-year-old man, treated with curative intent for histopathologically proven prostate cancer (initial prostate-specific antigen, 27 ng/mL; Gleason 4 + 5 = 9) through external beam radiation therapy in 2010 in combination with 3 years of androgen deprivation therapy (leuprorelin), underwent F-DCFPyL PET/CT for biochemical recurrence with a prostate-specific antigen of 4.1 ng/mL in February 2019. Multiple pelvic and some para-aortic lymph nodes showed highly increased F-DCFPyL uptake, suspicious for metastases. Incidentally, a solid mesenteric mass and mesenteric lymph nodes with moderately increased F-DCFPyL uptake were found. Upon histopathological evaluation, this proved to be a low-grade follicular lymphoma.
一位 75 岁男性，2010 年曾因组织病理学证实的前列腺癌（初始前列腺特异性抗原为 27ng/ml；Gleason 4+5=9）接受外照射放疗联合 3 年雄激素剥夺治疗（亮丙瑞林）进行根治性治疗，2019 年 2 月因前列腺特异性抗原为 4.1ng/ml 行 F-DCFPyL PET/CT 检查以排除生化复发。多个骨盆和一些腹主动脉旁淋巴结显示 F-DCFPyL 摄取高度增加，疑似转移。偶然发现肠系膜实性肿块和肠系膜淋巴结 F-DCFPyL 摄取中度增加。经组织病理学评估，证实为低度滤泡性淋巴瘤。
