Alaska Native Epidemiology Center, Alaska Native Tribal Health Consortium, Anchorage, Alaska (Drs Nash and Redwood); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington (Dr Peters); and School of Public Health, University of Washington, Seattle, Washington (Dr Peters).
J Public Health Manag Pract. 2019 Sep/Oct;25 Suppl 5, Tribal Epidemiology Centers: Advancing Public Health in Indian Country for Over 20 Years:S54-S60. doi: 10.1097/PHH.0000000000000994.
Alaska Native (AN) people have among the highest rates of colorectal cancer (CRC) recorded globally. Preventing CRC is an important health priority of AN tribal health leaders and communities. Lifestyle and genetic risk and protective factors for CRC among AN people remain understudied. We have been working to establish a tribally led, community-based, comprehensive investigation of lifestyle and genetic risk and protective factors for CRC among AN people. We describe the process of initiating this research study, including conversations with key tribal health system staff. We discuss themes that arose during these conversations and literature review and describe how those themes were used during the study design and protocol development phase. This description is intended to provide guidance to other researchers working to establish community-based studies of cancer risk, particularly among tribal communities.
阿拉斯加原住民 (AN) 人群的结直肠癌 (CRC) 发病率位居全球前列。预防 CRC 是 AN 部落卫生领导人及社区的一项重要健康重点。AN 人群中 CRC 的生活方式和遗传风险及保护因素仍研究不足。我们一直在努力建立一个部落主导、以社区为基础的针对 AN 人群 CRC 的生活方式和遗传风险及保护因素的综合调查。我们描述了启动这项研究的过程，包括与关键部落卫生系统工作人员的对话。我们讨论了这些对话和文献综述中出现的主题，并描述了如何在研究设计和方案制定阶段使用这些主题。这一描述旨在为其他研究人员提供指导，帮助他们开展癌症风险的基于社区的研究，特别是在部落社区中。
