Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom.
Am J Respir Crit Care Med. 2019 Nov 15;200(10):1228-1233. doi: 10.1164/rccm.201902-0297OC.
There is an aspiration to retain increasing numbers of older workers in employment, and strategies to achieve this need to make provision for the increasing prevalence of chronic diseases with age. There is a consistent body of cross-sectional evidence that suggests that patients with chronic obstructive pulmonary disease are more likely to have adverse employment outcomes. We report the findings of the first longitudinal study of this issue. We recruited full-time employed men and women in their 50s and followed them for a period of 18 months; we examined, after adjustment for potential confounders, the associations between breathlessness and airway obstruction at baseline and loss of employment in the intervening period. Among participants responding to the follow-up questionnaire (1,656 of 1,773 [93%]), the majority (78.5%) continued in full-time employment, but 10.6% were in part-time employment and 10.9% were no longer in paid employment. The adjusted risk of loss of employment was significantly increased for those with moderate or severe chronic obstructive pulmonary disease (risk ratio, 2.89; 95% confidence interval, 1.80-4.65) or breathlessness (risk ratio, 3.07; 95% confidence interval, 2.16-4.37) at baseline. There was no evident modification by sex or by manual/nonmanual work. Airway obstruction and breathlessness are independently associated with premature loss from the workforce in older workers; these observations provide strong support to the available cross-sectional evidence and suggest that interventions to help those with chronic obstructive pulmonary disease who wish to remain in work need to be tested.
人们渴望让越来越多的老年工人继续就业,实现这一目标的策略需要考虑到随着年龄增长慢性疾病发病率的上升。有大量横断面证据表明,慢性阻塞性肺疾病患者更有可能出现不良的就业结果。我们报告了首次对此问题进行的纵向研究的结果。我们招募了 50 多岁的全职在职男性和女性,并对他们进行了为期 18 个月的随访;我们在调整了潜在混杂因素后,考察了基线时呼吸困难和气道阻塞与随访期间失业之间的关联。在回应随访问卷的参与者中(1773 名中的 1656 名[93%]),大多数(78.5%)继续全职工作,但 10.6%从事兼职工作,10.9%不再从事有薪工作。与无慢性阻塞性肺疾病或轻度慢性阻塞性肺疾病相比,中度或重度慢性阻塞性肺疾病(风险比,2.89;95%置信区间,1.80-4.65)或基线时有呼吸困难(风险比,3.07;95%置信区间,2.16-4.37)的参与者失业的风险显著增加。性别或体力/非体力劳动对结果无明显影响。气道阻塞和呼吸困难与老年工人提前离开劳动力队伍独立相关;这些观察结果为现有的横断面证据提供了有力支持,并表明需要对旨在帮助那些希望继续工作的慢性阻塞性肺疾病患者的干预措施进行测试。