Vlahovich Kevin P, Sood Akshay
Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Pulm Ther. 2021 Jun;7(1):75-87. doi: 10.1007/s41030-020-00143-4. Epub 2020 Dec 31.
Occupational lung diseases (OLDs) are caused, aggravated or exacerbated by exposures at the workplace. OLDs encompass a wide range of respiratory diseases similar to that found outside the work environment. Occupational asthma is the most commonly diagnosed OLD. Other OLDs may include acute and chronic conditions, ranging from hypersensitivity pneumonitis to chronic obstructive pulmonary disease (COPD) to pulmonary fibrosis. Historically, research into OLDs has centered on diseases resulting from exposures relevant to high-income countries and more obvious hazardous occupations, such as silicosis in coal miners. Peer-reviewed publications in 2019 have broadened the focus to include low- and middle-income countries and once-overlooked occupations such as dry cleaning and animal husbandry. Technological advances and greater understanding of disease etiology have allowed researchers and clinicians to implement improved risk analysis, screening and mitigation strategies to not only treat disease once it occurs, but to identify at-risk populations and institute protections to prevent or limit the negative impacts of workplace hazards. As recognition of OLDs as a worldwide threat in a variety of occupations increases, research is allowing for the development of better treatments and preventive measures that advance workers' rights and ensure their continued good health.
职业性肺病(OLDs)是由工作场所的暴露所引起、加重或恶化的。职业性肺病包括一系列与工作环境之外发现的疾病相似的呼吸道疾病。职业性哮喘是最常被诊断出的职业性肺病。其他职业性肺病可能包括急性和慢性病症,从过敏性肺炎到慢性阻塞性肺疾病(COPD)再到肺纤维化。从历史上看,对职业性肺病的研究主要集中在与高收入国家相关的暴露以及更明显的危险职业所导致的疾病上,比如煤矿工人的矽肺病。2019年经过同行评审的出版物扩大了关注范围,将低收入和中等收入国家以及一些曾被忽视的职业(如干洗和畜牧业)纳入其中。技术进步以及对疾病病因的更深入理解使研究人员和临床医生能够实施改进的风险分析、筛查和缓解策略,不仅在疾病发生后进行治疗,还能识别高危人群并制定保护措施,以预防或限制工作场所危害的负面影响。随着人们越来越认识到职业性肺病是各种职业中的全球性威胁,相关研究推动了更好的治疗方法和预防措施的发展,这些措施有助于维护工人权利并确保他们持续保持良好健康状态。