Department of Infectious Disease, Public Health Service Amsterdam, Amsterdam, The Netherlands.
Department of Internal Medicine, Amsterdam Infection & Immunity Institute (AIII), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Hum Vaccin Immunother. 2020;16(1):126-127. doi: 10.1080/21645515.2019.1643679. Epub 2019 Jul 26.
When considering what the scientific evidence is for the potential added value to offer HPV vaccines to sex workers, not only its potential role for female sex workers should be examined, but its role for all those who conduct sex work. Our initial paper looked at the evidence in terms of HPV vaccine immunogenicity, efficacy, effect on transmission, induction of mucosal immunity, and not at implementation. Brown and Cabral considered our omission to address the aspects of implementation an 'academic mistake'. We disagree; implementation aspects are complex and require analyses of multiple barriers, and how to address these. It only makes sense to discuss these if there is scientific evidence for its implementation; otherwise offering the vaccine is not useful.
当考虑 HPV 疫苗对性工作者可能带来的附加价值的科学证据时,不仅应检查其对女性性工作者的潜在作用,还应检查其对所有从事性工作者的潜在作用。我们最初的论文研究了 HPV 疫苗的免疫原性、效力、对传播的影响、诱导黏膜免疫等方面的证据,而没有研究实施方面的证据。Brown 和 Cabral 认为我们没有考虑实施方面的内容是一个“学术错误”。我们不同意这一观点;实施方面非常复杂,需要分析多种障碍以及如何解决这些障碍。只有在有实施科学证据的情况下,讨论这些方面才有意义;否则提供疫苗是没有用的。