Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, China.
Int J Environ Res Public Health. 2019 Jul 25;16(15):2667. doi: 10.3390/ijerph16152667.
To explore the quality of life (QOL) status and related factors in young human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) aged 16 to 24 years in Zhejiang province.
A cross-sectional study was conducted in 22 counties of Zhejiang province, and 395 subjects took part in our research. A -test, one-way Analysis of variance (ANOVA), and multivariate stepwise linear regression analysis were used to investigate the factors associated with QOL in young HIV-infected MSM.
The total score on the QOL was 86.86 ± 14.01. The multivariate stepwise linear regression analysis revealed that self-efficacy and discrimination were associated with all domains on the QOL assessment, monthly income was associated with QOL for all domains except spirituality and consistent condom use during oral sex with men in the past three months was associated with QOL for all domains except the relationship domain. Those individuals within the group of young HIV-infected MSM who have higher self-efficacy, a higher monthly income, greater social support, safer sexual behaviors, a higher level of education, and a higher cluster of differentiation 4 (CD4) count have a better QOL.
These findings suggest that to improve the QOL of this population, greater emphasis should be placed on improving social support, self-efficacy, and antiviral therapy adherence and on reducing discrimination, disease progression, and high-risk behaviors.
探讨浙江省 16-24 岁青年男性同性恋 HIV 感染者的生活质量（QOL）状况及其相关因素。
采用横断面研究，在浙江省 22 个县抽取 395 名研究对象，采用 -检验、单因素方差分析（ANOVA）和多元逐步线性回归分析方法，探讨与青年 HIV 感染男男性行为者生活质量相关的因素。
QOL 总分 86.86±14.01。多元逐步线性回归分析显示，自我效能和歧视与生活质量各领域均相关，月收入与生活质量各领域均相关，除精神领域外，近 3 个月与男性发生口腔性行为时坚持使用安全套与生活质量各领域均相关，除关系领域外。在青年 HIV 感染男男性行为者中，自我效能较高、月收入较高、社会支持较大、性行为较安全、教育程度较高、CD4 聚类分化较高的个体生活质量较好。
这些发现表明，为了提高该人群的生活质量，应更加重视提高社会支持、自我效能和抗病毒治疗依从性，减少歧视、疾病进展和高危行为。
