First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Emergency Department, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
BMJ Open. 2019 Jul 26;9(7):e028771. doi: 10.1136/bmjopen-2018-028771.
Chronic heart failure (CHF) is defined when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs, and it is caused by various cardiopulmonary diseases. CHF is a common, lifelong and costly condition. Baduanjin exercise (BDJE), a form of traditional Chinese regimen, has been integrated into China's clinical practice in recent years and has shown promise in cardiac rehabilitation of CHF patients. However, the efficacy of BDJE on CHF patients has not been fully statistically evaluated. In this study, we aim to systematically examine the efficacy and safety of BDJE for CHF patients.
A systematic literature search for articles up to October 2018 will be conducted in the following databases: Web of Science, Pubmed, Embase, Cochrane Library, Chinese Science and Technology Periodicals Database, Chinese National Knowledge Infrastructure and Wanfang Database. We will also search other resources. Randomised controlled trials that examined treatment of CHF patients with BDJE will be selected. Results will be analysed by assessing the quality of life of patients using the Minnesota living with heart failure questionnaire, and measurement of distance walked over a span of 6 min in the 6 min walk test. RevMan 5.3 will be used for data synthesis, sensitivity analysis, meta-regression analysis, subgroup analysis and risk of bias assessment. A funnel plot will be developed to evaluate reporting bias, and Begg and Egger tests will be used to assess funnel plot symmetries. Grading of recommendations assessment, development and evaluation system will be utilised to assess the quality of evidence.
This systematic review will be submitted to a peer-reviewed journal.
CRD42018114672.
当心脏无法充分泵血以满足身体需求时,就会出现慢性心力衰竭(CHF),这是由各种心肺疾病引起的。CHF 是一种常见的、终身的且昂贵的疾病。八段锦运动(BDJE),一种传统的中医养生法,近年来已被纳入中国的临床实践,并在 CHF 患者的心脏康复中显示出前景。然而,BDJE 对 CHF 患者的疗效尚未得到充分的统计学评估。在这项研究中,我们旨在系统地评估 BDJE 对 CHF 患者的疗效和安全性。
我们将对截至 2018 年 10 月的以下数据库中的文献进行系统检索:Web of Science、Pubmed、Embase、Cochrane 图书馆、中国科学技术期刊数据库、中国国家知识基础设施和万方数据库。我们还将搜索其他资源。将选择随机对照试验,研究 BDJE 治疗 CHF 患者的效果。结果将通过使用明尼苏达州心力衰竭生活质量问卷评估患者的生活质量,以及在 6 分钟步行试验中测量 6 分钟内行走的距离来分析。RevMan 5.3 将用于数据综合、敏感性分析、meta 回归分析、亚组分析和偏倚风险评估。将开发漏斗图以评估报告偏倚,并使用 Begg 和 Egger 检验评估漏斗图的对称性。将使用推荐评估、制定和评估系统(Grading of Recommendations Assessment, Development and Evaluation system,GRADE)评估证据质量。
本系统评价将提交给同行评议期刊。
CRD42018114672。