Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Zurich, Binzmühlestrasse 14/ 26, 8050, Zürich, Switzerland.
Arch Womens Ment Health. 2020 Jun;23(3):391-399. doi: 10.1007/s00737-019-00990-4. Epub 2019 Jul 26.
The main objective of the present study was to report the incidence, recurrence, prevalence, and course of depressive symptoms during the transition from late pregnancy to the postpartum period in healthy women with and without a history of depression. The study also aimed to examine the predictive value of a history of premenstrual syndrome (PMS)/premenstrual dysphoric disorder (PMDD) for peripartum depressive symptoms. A sample of 687 healthy women with (n = 192) and without (n = 495) a history of depression were included in the present analyses. Maternal depressive symptoms were assessed during late pregnancy, 1-2 weeks postpartum, and 4-6 weeks postpartum using the German version of the Edinburgh Postnatal Depression Scale. PMS/PMDD was assessed retrospectively using the German version of the Premenstrual Symptoms Screening Tool. Women with a history of depression were twice more likely to show peripartum depressive symptoms than women without a history of depression. A history of symptoms of PMS/PMDD prior to the current pregnancy was associated with increased odds of peripartum depressive symptoms (p values < .05). Peripartum depressive symptoms are highly prevalent, especially in women with a history of depression and co-existing symptoms of PMS/PMDD. Screening for depression in the antenatal period is highly recommended, particularly for individuals with previous PMS/PMDD or a history of depression.
本研究的主要目的是报告在没有和有抑郁史的健康女性中，从妊娠晚期到产后期间抑郁症状的发生率、复发率、患病率和病程。本研究还旨在探讨经前期综合征（PMS）/经前期烦躁障碍（PMDD）病史对围产期抑郁症状的预测价值。本分析纳入了 687 名有（n=192）和没有（n=495）抑郁史的健康女性。在妊娠晚期、产后 1-2 周和产后 4-6 周使用德国版爱丁堡产后抑郁量表评估产妇抑郁症状。使用德国版经前期症状筛查工具回顾性评估 PMS/PMDD。有抑郁史的女性出现围产期抑郁症状的可能性是没有抑郁史的女性的两倍。在当前妊娠前有 PMS/PMDD 症状史与围产期抑郁症状的几率增加相关（p 值<.05）。围产期抑郁症状非常普遍，尤其是在有抑郁史和共存 PMS/PMDD 症状的女性中。强烈建议在产前期间进行抑郁筛查，特别是对于有 PMS/PMDD 病史或抑郁病史的个体。
