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夫妇围产期抑郁的早期检测:一项单中心前瞻性研究。

Early detection of perinatal depression in couples: a single-center prospective study.

机构信息

Service de Gynécologie-Obstétrique, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Université Lyon 1 Claude Bernard, Lyon, France.

Service de Gynécologie-Obstétrique, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Université Lyon 1 Claude Bernard, Lyon, France.

出版信息

Eur Psychiatry. 2024 Sep 3;67(1):e48. doi: 10.1192/j.eurpsy.2024.1755.

DOI:10.1192/j.eurpsy.2024.1755
PMID:39225230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11441343/
Abstract

OBJECTIVE

This prospective study aimed to assess couples' psychological status during the perinatal period to identify those at risk for postpartum depression.

METHODS

Conducted at Lyon University Hospital from March to July 2022, the study enrolled pregnant women without progressive psychiatric disorders or obstetric risk factors, and their partners. Participants completed the Edinburgh Postnatal Depression Scale (EPDS) at three points: during the 9th month of pregnancy, immediate postpartum, and 6-8 weeks after delivery. A score ≥10 on the EPDS indicated depression risk. A score ≥10 on the EPDS indicate depression risk. The primary endpoint was EPDS scores throughout the perinatal period.

RESULTS

Ninety-five couples participated; 96% of patients and 68% of partners completed pre-delivery questionnaires, 81% and 71% during maternity stay, and 64% and 46% postpartum, respectively. Overall, 15% of patients and 1% of partners had EPDS scores >10 in the postpartum period. Psychiatric history and emergency cesarean sections were associated with higher immediate postpartum EPDS scores in patients [Beta 3.7 points, 95% CI 0.91; 6.4 and Beta 5.2 points, 2.2; 8.1, respectively]. Episiotomy was associated with higher EPDS scores in partners. No significant association between the different factors studied and the EPDS score was found at 6-8 weeks postpartum in patients nor their partners.

CONCLUSIONS

While specific risk factors for persistent perinatal depression in couples were not identified, a notable proportion of patients exhibited high EPDS scores. Screening all couples during prepartum and postpartum periods is crucial, regardless of identified risk factors.

摘要

目的

本前瞻性研究旨在评估围产期夫妇的心理状况,以确定那些有产后抑郁风险的夫妇。

方法

该研究于 2022 年 3 月至 7 月在里昂大学医院进行,纳入了无进展性精神疾病或产科危险因素的孕妇及其伴侣。参与者在三个时间点完成爱丁堡产后抑郁量表(EPDS):妊娠第 9 个月、产后即刻和产后 6-8 周。EPDS 得分≥10 表示有抑郁风险。主要终点是围产期 EPDS 评分。

结果

95 对夫妇参与了研究;96%的患者和 68%的伴侣完成了产前问卷,81%和 71%在分娩期间,64%和 46%在产后。总体而言,15%的患者和 1%的伴侣在产后 EPDS 评分>10。患者的精神病史和紧急剖宫产与产后即刻 EPDS 评分较高相关[患者的 Beta 3.7 分,95%CI 0.91; 6.4 和 Beta 5.2 分,2.2; 8.1]。会阴切开术与伴侣的 EPDS 评分较高相关。在产后 6-8 周,患者及其伴侣的 EPDS 评分与研究中不同因素之间均未发现显著相关性。

结论

尽管未确定夫妇持续性围产期抑郁的特定风险因素,但相当一部分患者的 EPDS 评分较高。无论是否存在已知的风险因素,在产前和产后期间对所有夫妇进行筛查至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/c37304d75156/S0924933824017553_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/971856470ff8/S0924933824017553_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/dd2bcc262f97/S0924933824017553_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/c37304d75156/S0924933824017553_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/971856470ff8/S0924933824017553_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/dd2bcc262f97/S0924933824017553_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/11441343/c37304d75156/S0924933824017553_fig3.jpg

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本文引用的文献

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JAMA Netw Open. 2022 Jun 1;5(6):e2218969. doi: 10.1001/jamanetworkopen.2022.18969.
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Int J Environ Res Public Health. 2022 Apr 18;19(8):4900. doi: 10.3390/ijerph19084900.
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产前诊断对母婴二元组互动的影响:生命第一年产前护理的纵向研究。
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Early Association Factors for Depression Symptoms in Pregnancy: A Comparison between Spanish Women Spontaneously Gestation and with Assisted Reproduction Techniques.孕期抑郁症状的早期相关因素:西班牙自然受孕女性与接受辅助生殖技术女性的比较
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