Department of Pediatrics, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan.
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
J Pediatr. 2019 Nov;214:227-230. doi: 10.1016/j.jpeds.2019.06.018. Epub 2019 Jul 24.
Compared with a 5% intravenous immunoglobulin, a 10% intravenous immunoglobulin as the first-line treatment of Kawasaki disease significantly reduced the fever duration (10 vs 13 hours, P = .022) among the responders, and the interval to adjunctive therapy for nonresponders (47 vs 49 hours, P = .035). There were no severe adverse events.
与 5%静脉注射免疫球蛋白相比，10%静脉注射免疫球蛋白作为川崎病的一线治疗药物，可显著缩短（P=0.022）应答者的发热时间（10 小时 vs 13 小时），同时也缩短（P=0.035）无应答者的辅助治疗间隔时间（47 小时 vs 49 小时）。没有严重的不良事件。
