Head and Neck Institute, Department of Otolaryngology-Head and Neck Surgery, Cleveland Clinic, Cleveland, OH, United States of America.
Head and Neck Institute, Department of Otolaryngology-Head and Neck Surgery, Cleveland Clinic, Cleveland, OH, United States of America.
Am J Otolaryngol. 2019 Nov-Dec;40(6):102262. doi: 10.1016/j.amjoto.2019.07.006. Epub 2019 Jul 8.
To evaluate the use of the anterolateral thigh fascia free flap for use in neovascularization of mandibular bone in moderate osteoradionecrosis (ORN). All patients had ORN secondary to prior radiation therapy that was not severe enough to warrant segmental resection and reconstruction.
Case series.
Tertiary medical center.
IRB approval was obtained, and a retrospective chart review performed of all mandibular rescue procedures performed from 2011 to 2014. Patients with a minimum of two years of follow-up were included in the study.
All surgeries were performed by the senior surgeon (MF). Eight patients underwent the mandibular rescue procedure with resolution of pain and return to oral feeding in all patients, and no evidence of ORN progression on follow-up imaging. A total of 9 ALT free flaps were performed (one patient had 2 surgeries). Gender was distributed evenly (4 female/4 male). The average age was 66 (58-78), average length of hospitalization was 2.8 days (1-7), and average follow-up was 46.5 months (25-63).
The mandibular rescue procedure is a novel technique using the ALT fascia lata free flap to provide coverage and nutrient blood flow to mandible devascularized secondary to radiation therapy. The flap provides the advantages of low morbidity, ease of harvest, two-team approach to ablation and reconstruction, and quick recovery resulting in 'short-stay' free flap surgery. Although conclusions must be tempered in this small case series, our early clinical experience shows the ALT fascia lata flap holds promise in halting the destructive progression of ORN that is not yet advanced enough to require a segmental resection and reconstruction.
评估股前外侧筋膜游离皮瓣在中度放射性骨坏死(ORN)下颌骨新血管生成中的应用。所有患者均因先前的放射治疗而继发 ORN,但严重程度不足以需要节段切除和重建。
病例系列。
三级医疗中心。
获得 IRB 批准,并对 2011 年至 2014 年期间进行的所有下颌骨挽救手术进行回顾性图表审查。研究纳入至少随访 2 年的患者。
所有手术均由资深外科医生(MF)进行。8 例患者接受了下颌骨挽救手术,所有患者均缓解了疼痛并恢复了经口进食,且随访影像学未见 ORN 进展。共进行了 9 次 ALT 游离皮瓣手术(1 例患者进行了 2 次手术)。性别分布均匀(4 女/4 男)。平均年龄为 66 岁(58-78 岁),平均住院时间为 2.8 天(1-7 天),平均随访时间为 46.5 个月(25-63 个月)。
下颌骨挽救手术是一种使用 ALT 阔筋膜游离皮瓣提供覆盖和营养血流的新技术,用于治疗因放射治疗而导致的下颌骨缺血。该皮瓣具有以下优点:发病率低、易于采集、消融和重建采用双团队方法,以及快速恢复,从而实现“短期停留”游离皮瓣手术。尽管在这个小病例系列中必须谨慎得出结论,但我们的早期临床经验表明,ALT 阔筋膜皮瓣有望阻止 ORN 的破坏性进展,而这种进展还没有严重到需要进行节段切除和重建的程度。