Department of Oral and Maxillofacial Surgery (Head: Prof. Dr. Dr. K.-D. Wolff), Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
Department of Oral and Maxillofacial Surgery (Head: Prof. Dr. Dr. K.-D. Wolff), Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
J Craniomaxillofac Surg. 2018 Jan;46(1):148-154. doi: 10.1016/j.jcms.2017.09.025. Epub 2017 Nov 2.
Osteoradionecrosis (ORN) of the jaws represents one of the most severe complications after primary or adjuvant radiation therapy (RT) of large head and neck tumors. In advanced ORN cases, surgical management is generally considered the therapy of choice. However, in several severe ORN patients with extensive bone and soft tissue defects, functional and aesthetic reconstruction represents a huge challenge for any surgeon, with an increased risk of post-operative wound healing disorders. Our aim here was to perform a double free flap technique as a therapeutic option in this difficult patient collective and to evaluate the post-operative outcome.
15 patients with advanced and severe ORN undergoing mandibular and soft tissue reconstruction with a double free flap were retrospectively reviewed. In one single operation involving a three-team approach, an obligatory free fibular flap (FFF) was freely combined with another free flap according to the desired features: anterolateral thigh (ALT) or vastus lateralis flap (VLF), radial forearm flap (RFF) and latissimus dorsi flap (LDF).
We found sufficient wound healing in the head and neck region in all patients with no need for any additional surgical intervention. The overall flap success rate was 93.3%, although three revisions of anastomosis were necessary. Furthermore, prolonged stay on the intensive care unit (ICU) and extended hospitalisation were avoided.
The double free flap technique with an obligatory FFF provides a suitable surgical solution for the treatment of patients with severe ORN of the mandibular bone for which other conservative or surgical therapy strategies have reached their limits.
颌骨放射性骨坏死(ORN)是头颈部大肿瘤原发或辅助放疗后最严重的并发症之一。在晚期 ORN 病例中,手术治疗通常被认为是首选治疗方法。然而,在一些严重 ORN 患者中,广泛的骨和软组织缺损给任何外科医生的功能和美学重建带来了巨大挑战,增加了术后伤口愈合障碍的风险。我们的目的是在这个困难的患者群体中采用双游离皮瓣技术作为一种治疗选择,并评估术后结果。
回顾性分析了 15 例接受下颌骨和软组织重建的晚期和严重 ORN 患者,采用双游离皮瓣。在一个涉及三队合作的单一手术中,强制性游离腓骨皮瓣(FFF)根据所需特征与另一个游离皮瓣自由结合:股前外侧皮瓣(ALT)或股外侧肌皮瓣(VLF)、桡侧前臂皮瓣(RFF)和背阔肌皮瓣(LDF)。
所有患者的头颈部均有足够的伤口愈合,无需任何额外的手术干预。总的皮瓣成功率为 93.3%,尽管需要进行三次吻合修正。此外,避免了长时间在重症监护病房(ICU)和延长住院时间。
对于其他保守或手术治疗策略已达到极限的下颌骨严重 ORN 患者,强制性 FFF 的双游离皮瓣技术提供了一种合适的手术解决方案。