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双侧同期与分期全膝关节置换术:围手术期风险差异极小。

Bilateral Simultaneous vs Staged Total Knee Arthroplasty: Minimal Difference in Perioperative Risks.

机构信息

Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA.

出版信息

J Arthroplasty. 2019 Dec;34(12):2944-2949.e1. doi: 10.1016/j.arth.2019.07.002. Epub 2019 Jul 5.

Abstract

BACKGROUND

With the rising utilization of total joint arthroplasty, the role of simultaneous-bilateral surgery will have an expanding impact. The purpose of this study is to examine the risks of perioperative complications with this approach in total knee arthroplasty (TKA), to inform shared decision-making.

METHODS

We reviewed national hospital discharge data from 2005 to 2014 to compare outcomes between simultaneous-bilateral TKAs (sim-BTKAs) and staged-bilateral TKAs (staged-BTKAs). Hierarchical logistic regression analyses were used to adjust for confounders. Outcomes analyzed included mortality, various medical complications, knee infection, and mechanical complications.

RESULTS

This study analyzed 27,301 sim-BTKAs and 45,419 staged-BTKAs. Patients who underwent simultaneous surgery had a statistically significant higher adjusted odds of mortality, cardiac events, thromboembolic events, and complications involving the urinary and digestive systems, and a lower adjusted odds of deep knee infection and hematoma. Thirteen of the 14 complications had overall incidences less than 2% and 1 outcome had an incidence of 3%. The absolute between-group risk difference for any complication was 1% or less.

CONCLUSION

Sim-BTKAs have a statistically significant increased odds of multiple complications compared to staged-BTKAs. However, the absolute risk differences between these options are minimal and the occurrence of any complication is low.

LEVEL OF EVIDENCE

Therapeutic Level III.

摘要

背景

随着全关节置换术使用率的上升,同期双侧手术的作用将产生更大的影响。本研究旨在研究同期双侧全膝关节置换术(sim-BTKAs)的围手术期并发症风险,为共同决策提供信息。

方法

我们回顾了 2005 年至 2014 年的全国住院数据,比较了同期双侧全膝关节置换术(sim-BTKAs)和分期双侧全膝关节置换术(分期-BTKAs)的结果。使用分层逻辑回归分析调整混杂因素。分析的结果包括死亡率、各种医疗并发症、膝关节感染和机械并发症。

结果

本研究分析了 27301 例同期双侧全膝关节置换术和 45419 例分期双侧全膝关节置换术。同期手术的患者死亡率、心脏事件、血栓栓塞事件以及涉及泌尿和消化系统的并发症的调整后优势比具有统计学意义,而深部膝关节感染和血肿的调整后优势比较低。14 种并发症中有 13 种的总发生率低于 2%,1 种并发症的发生率为 3%。任何并发症的组间绝对风险差异为 1%或更小。

结论

与分期双侧全膝关节置换术相比,同期双侧全膝关节置换术的并发症发生风险具有统计学意义的增加。然而,这些选择之间的绝对风险差异很小,任何并发症的发生几率都很低。

证据水平

治疗性 III 级。

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