心-股动脉袖带脉搏波速度：一种新的动脉僵硬度非技术测量指标。

Heart-Thigh Cuff Pulse Wave Velocity: A Novel Nontechnical Measure of Arterial Stiffness.

机构信息

Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA.

出版信息

Am J Hypertens. 2019 Oct 16;32(11):1051-1053. doi: 10.1093/ajh/hpz124.

DOI:10.1093/ajh/hpz124

PMID:31352485

Abstract

BACKGROUND

Recently, a novel index of arterial stiffness was developed to eliminate the placements of transducers on the carotid and femoral arteries and to make the measurement substantially easier. We evaluated the agreement of this new methodology with the well-established carotid-femoral pulse wave velocity (cfPWV).

METHODS

A total of 50 adults (28 men and 22 women) varying widely in age and blood pressure were studied. Heart-thigh pulse wave velocity (htPWV) and cfPWV were measured and compared.

RESULTS

Mean values of cfPWV and htPWV were 713 ± 145 and 699 ± 150 cm/s and were not significantly different (P = 0.43). Both cfPWV and htPWV were significantly associated with age (r = 0.80 and 0.58), body mass index (r = 0.44 and 0.31), and systolic blood pressure (r = 0.42 and 0.41). The 2 pulse wave velocity measures demonstrated a strong linear association with a Pearson correlation coefficient of 0.64 (P < 0.001). This agreement was consistent with the results of the Bland-Altman plot.

CONCLUSION

The automatic htPWV method, which permits the data acquisition with minimum technical skill, time, and intrusion in an operator-independent fashion, has good potential as a screening device for assessing arterial stiffness in a clinical setting.

摘要

背景

最近，一种新的动脉僵硬度指标被开发出来，以消除在颈动脉和股动脉上放置换能器的需要，并使测量变得更加容易。我们评估了这种新方法与已建立的颈动脉-股动脉脉搏波速度（cfPWV）的一致性。

方法

共纳入了 50 名年龄和血压差异很大的成年人（28 名男性和 22 名女性）。测量了心-股脉搏波速度（htPWV）和 cfPWV，并进行了比较。

结果

cfPWV 和 htPWV 的平均数值分别为 713±145cm/s 和 699±150cm/s，两者无显著差异（P=0.43）。cfPWV 和 htPWV 均与年龄（r=0.80 和 0.58）、体重指数（r=0.44 和 0.31）和收缩压（r=0.42 和 0.41）显著相关。这两种脉搏波速度测量值具有很强的线性相关性，皮尔逊相关系数为 0.64（P<0.001）。这种一致性与 Bland-Altman 图的结果一致。