Lee Victoria S, Lin Sandra Y
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Outpatient Center, 6th Floor, 601 North Caroline Street, Baltimore, MD 21287-0910, USA.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Outpatient Center, 6th Floor, 601 North Caroline Street, Baltimore, MD 21287-0910, USA.
Otolaryngol Clin North Am. 2019 Oct;52(5):863-873. doi: 10.1016/j.otc.2019.05.005. Epub 2019 Jul 26.
Food allergy and allergic rhinitis are childhood diseases with special relevance to the pediatric otolaryngologist. Much of the diagnosis of food allergy can be made on history alone; strict avoidance is the mainstay treatment. Skin prick testing and serum-specific IgE testing play a stronger role in allergic rhinitis diagnosis. If pharmacotherapy fails, allergen immunotherapy is an option. Currently, there is intense investigation on diagnostic tests, novel treatments, and prevention strategies that could dramatically affect the way these diseases are identified and managed. This article summarizes the epidemiology, pathophysiology, diagnosis, and management of food allergy and allergic rhinitis.
食物过敏和过敏性鼻炎是与儿科耳鼻喉科医生密切相关的儿童疾病。食物过敏的诊断很大程度上仅凭病史即可做出;严格避免是主要的治疗方法。皮肤点刺试验和血清特异性IgE检测在过敏性鼻炎的诊断中发挥着更重要的作用。如果药物治疗无效,变应原免疫疗法是一种选择。目前,对于可能会显著影响这些疾病的诊断和管理方式的诊断测试、新型治疗方法和预防策略正在进行深入研究。本文总结了食物过敏和过敏性鼻炎的流行病学、病理生理学、诊断和管理。