Azizian Zahra, Behrangi Elham, Hasheminasabzavareh Roshanak, Kazemlo Hassan, Esmaeeli Roja, Hassani Parvaneh
Iran University of Medical Sciences, Tehran, Iran.
College of Engineering, University of Alzahra, Tehran, Iran.
Adv Prev Med. 2019 Jul 1;2019:5293193. doi: 10.1155/2019/5293193. eCollection 2019.
Diabetes mellitus (DM) is an interdisciplinary disorder that needs many different specialties' attention; however, the importance of dermatologists' knowledge has not been highlighted regarding this issue. As a result, we aim to assess the prevalence and variety of DM skin and nail manifestations in an effort to further acquaint dermatologists and other clinicians with diabetic dermatologic manifestations.
This was a cross-sectional study; subjects who had a diagnosis of DM, attending to the outpatient endocrinology clinics of Rassoul Akram Hospital, Tehran, Iran, were evaluated by one dermatologist for diabetic dermopathy. The results were recorded in prepared data sheets, and general descriptions of DM duration, DM type, DM control, and drug history as well as the demographic data were gathered.
Among a total of 255 subjects, the prevalence of one or more identifiable skin conditions was 88.4%. 15.7% of the subjects had nail manifestations. Among cutaneous manifestations, acanthosis nigricans, acral erythema, and onychoschizia showed a significant relationship with the age and disease duration (p<0.05); and knuckle pebbles, eczema, facial erythema, and koilonychias had a meaningful relationship with FBS level and glycated hemoglobin, HbA1c (p<0.05).
This study provides an overview that facilitates earlier detection and treatment of DM. Also, this data can help physicians and endocrinologists to visualize DM control level.
糖尿病（DM）是一种需要多学科关注的综合性疾病；然而，皮肤科医生在此问题上的知识重要性尚未得到凸显。因此，我们旨在评估糖尿病皮肤和指甲表现的患病率及种类，以便让皮肤科医生和其他临床医生进一步了解糖尿病的皮肤表现。
这是一项横断面研究；在伊朗德黑兰拉苏勒·阿克拉姆医院门诊内分泌科就诊且被诊断为糖尿病的患者，由一名皮肤科医生对其糖尿病性皮肤病进行评估。结果记录在准备好的数据表中，并收集了糖尿病病程、糖尿病类型、糖尿病控制情况、用药史以及人口统计学数据的总体描述。
在总共255名受试者中，一种或多种可识别皮肤状况的患病率为88.4%。15.7%的受试者有指甲表现。在皮肤表现中，黑棘皮病、肢端红斑和甲裂与年龄和病程有显著相关性（p<0.05）；指节垫、湿疹、面部红斑和匙状甲与空腹血糖水平和糖化血红蛋白HbA1c有显著相关性（p<0.05）。
本研究提供了一个概述，有助于糖尿病的早期发现和治疗。此外，这些数据可以帮助医生和内分泌学家了解糖尿病的控制水平。
