• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

糖尿病相关皮肤表现——一项回顾性研究

Cutaneous Manifestations Associated with Diabetes Mellitus-A Retrospective Study.

作者信息

Vâță Dan, Stanciu Diana-Elena, Temelie-Olinici Doinița, Porumb-Andrese Elena, Tarcău Bogdan-Marian, Grecu Vasile-Bogdan, Gheucă-Solovăstru Laura

机构信息

Department of Dermatology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.

Dermatology Clinic, "St. Spiridon" Emergency County Hospital, 700106 Iasi, Romania.

出版信息

Diseases. 2023 Aug 18;11(3):106. doi: 10.3390/diseases11030106.

DOI:10.3390/diseases11030106
PMID:37606477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10443279/
Abstract

Diabetes mellitus (DM) is one of the world's most important health problems, affecting more than half a billion of the world's population today, with an ever-increasing prevalence. Among the most common manifestations of diabetes are skin manifestations, with 30-70% of patients experiencing skin complications during the course of the disease. Conditions such as acanthosis nigricans, diabetic dermopathy, necrobiosis lipoidica, bacterial infections, fungal infections, skin xerosis, and metabolic prurigo are often associated with diabetes and often precede its diagnosis. We conducted a retrospective study on a group of 103 patients hospitalized between January 2018 and December 2022, in a clinic of a county hospital, using as criteria the diagnosis of diabetes mellitus complicated by cutaneous manifestations frequently associated with diabetes. The aim was to observe which are the most common manifestations and whether they correlate with data in the research literature. In the present study, manifestations such as diabetic foot (20% of patients), bacterial (35%) and fungal infections, and cutaneous xerosis (45%) were predominant. Often, the integumentary involvement may precede the diagnosis of the underlying disease. It is therefore very important to recognize, investigate and treat these manifestations as soon as possible.

摘要

糖尿病(DM)是全球最重要的健康问题之一,目前影响着全球超过5亿人口,且患病率不断上升。糖尿病最常见的表现之一是皮肤表现,30%-70%的患者在疾病过程中会出现皮肤并发症。黑棘皮病、糖尿病性皮肤病、类脂质渐进性坏死、细菌感染、真菌感染、皮肤干燥症和代谢性瘙痒等病症常与糖尿病相关,且往往在糖尿病诊断之前出现。我们对2018年1月至2022年12月期间在一家县级医院诊所住院的103名患者进行了一项回顾性研究,以糖尿病合并常见皮肤表现的诊断为标准。目的是观察哪些是最常见的表现,以及它们是否与研究文献中的数据相关。在本研究中,糖尿病足(20%的患者)、细菌感染(35%)、真菌感染和皮肤干燥症(45%)等表现最为突出。通常,皮肤受累可能先于潜在疾病的诊断。因此,尽快识别、调查和治疗这些表现非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1134/10443279/1a9623e40d6d/diseases-11-00106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1134/10443279/1a9623e40d6d/diseases-11-00106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1134/10443279/1a9623e40d6d/diseases-11-00106-g001.jpg

相似文献

1
Cutaneous Manifestations Associated with Diabetes Mellitus-A Retrospective Study.糖尿病相关皮肤表现——一项回顾性研究
Diseases. 2023 Aug 18;11(3):106. doi: 10.3390/diseases11030106.
2
Cutaneous alterations in diabetes mellitus.糖尿病的皮肤改变
Wounds. 2011 Jul;23(7):192-203.
3
Cutaneous Manifestations of Diabetes.糖尿病的皮肤表现。
Med Clin North Am. 2021 Jul;105(4):681-697. doi: 10.1016/j.mcna.2021.04.008.
4
Diabetes mellitus.糖尿病
Clin Dermatol. 2006 Jul-Aug;24(4):237-46. doi: 10.1016/j.clindermatol.2006.04.009.
5
A clinical study of dermatoses in diabetes to establish its markers.一项关于糖尿病皮肤病变以确定其标志物的临床研究。
Indian J Dermatol. 2012 Jan;57(1):20-5. doi: 10.4103/0019-5154.92671.
6
Dermatologic manifestations of diabetes mellitus: a review.糖尿病的皮肤表现:综述。
Endocrinol Metab Clin North Am. 2013 Dec;42(4):869-98. doi: 10.1016/j.ecl.2013.07.004.
7
Cutaneous manifestations in children with diabetes mellitus and obesity.糖尿病和肥胖儿童的皮肤表现
Actas Dermosifiliogr. 2014 Jul-Aug;105(6):546-57. doi: 10.1016/j.ad.2013.11.014. Epub 2014 Mar 31.
8
Diabetes-associated dermatological manifestations in primary care and their association with vascular complications.基层医疗中糖尿病相关的皮肤表现及其与血管并发症的关联。
J Diabetes Metab Disord. 2020 Sep 16;19(2):989-996. doi: 10.1007/s40200-020-00594-1. eCollection 2020 Dec.
9
Cutaneous disorders in 500 diabetic patients attending diabetic clinic.500名前往糖尿病门诊的糖尿病患者的皮肤疾病
Indian J Dermatol. 2011 Mar;56(2):160-4. doi: 10.4103/0019-5154.80409.
10
[Skin symptoms in diabetic metabolism].[糖尿病代谢中的皮肤症状]
Ther Umsch. 1995 Apr;52(4):264-8.

引用本文的文献

1
Association of Dermatological Manifestations in Patients With Type 2 Diabetes Mellitus With Respect to Duration of Diabetes.2型糖尿病患者皮肤表现与糖尿病病程的相关性
Cureus. 2025 Jul 24;17(7):e88681. doi: 10.7759/cureus.88681. eCollection 2025 Jul.
2
Recurrent Urinary Tract Infection in Diabetics: A Retrospective Analysis.糖尿病患者复发性尿路感染:一项回顾性分析。
Cureus. 2025 Jul 13;17(7):e87816. doi: 10.7759/cureus.87816. eCollection 2025 Jul.
3
Association of Dyslipidemia With Dermatological Manifestations in Patients With Type 2 Diabetes Mellitus.

本文引用的文献

1
Characteristics of ulcerated and non-ulcerated necrobiosis lipoidica.溃疡性和非溃疡性坏死性脂膜炎的特征。
Int J Dermatol. 2023 Jun;62(6):790-796. doi: 10.1111/ijd.16529. Epub 2022 Dec 7.
2
Optimization of Extraction Process of Polysaccharides MAP-2 from Opuntia Milpa Alta by Response Surface Methodology and Evaluation of Its Potential as α-Glucosidase Inhibitor.响应面法优化米邦塔仙人掌中多糖MAP-2的提取工艺及其作为α-葡萄糖苷酶抑制剂的潜力评估
Foods. 2022 Nov 6;11(21):3530. doi: 10.3390/foods11213530.
3
Prevalence of Onychomycosis in Diabetic Patients: A Case-Control Study Performed at University Hospital Policlinico in Catania.
2型糖尿病患者血脂异常与皮肤表现的关联
Cureus. 2025 Jun 14;17(6):e86030. doi: 10.7759/cureus.86030. eCollection 2025 Jun.
4
A Comparative Analysis of Clinical Features of Diabetes Mellitus Type 2 With Respect to Duration of Diabetes.2型糖尿病临床特征与糖尿病病程的比较分析
Cureus. 2024 Nov 30;16(11):e74849. doi: 10.7759/cureus.74849. eCollection 2024 Nov.
5
Comprehensive Review of the Latest Investigations of the Health-Enhancing Effects of Selected Properties of and Microalgae on Skin.对特定微藻特性对皮肤健康促进作用的最新研究综述
Pharmaceuticals (Basel). 2024 Oct 3;17(10):1321. doi: 10.3390/ph17101321.
6
Pathology of Diabetes-Induced Immune Dysfunction.糖尿病引起的免疫功能障碍的病理学
Int J Mol Sci. 2024 Jun 28;25(13):7105. doi: 10.3390/ijms25137105.
7
The Intersection of Dermatological Dilemmas and Endocrinological Complexities: Understanding Necrobiosis Lipoidica-A Comprehensive Review.皮肤病难题与内分泌复杂性的交叉:了解脂性渐进性坏死——一篇综述
Biomedicines. 2024 Feb 1;12(2):337. doi: 10.3390/biomedicines12020337.
糖尿病患者甲癣的患病率:在卡塔尼亚大学综合医院进行的一项病例对照研究。
J Fungi (Basel). 2022 Aug 30;8(9):922. doi: 10.3390/jof8090922.
4
Itch in Adult Population with Type 2 Diabetes Mellitus: Clinical Profile, Pathogenesis and Disease-Related Burden in a Cross-Sectional Study.2型糖尿病成年患者的瘙痒:一项横断面研究中的临床特征、发病机制及疾病相关负担
Biology (Basel). 2021 Dec 15;10(12):1332. doi: 10.3390/biology10121332.
5
Molecular markers associated with potentially malignant oral lesions (Review).与潜在恶性口腔病变相关的分子标志物(综述)
Exp Ther Med. 2021 Aug;22(2):834. doi: 10.3892/etm.2021.10266. Epub 2021 Jun 4.
6
Cutaneous Manifestations of Diabetes.糖尿病的皮肤表现。
Med Clin North Am. 2021 Jul;105(4):681-697. doi: 10.1016/j.mcna.2021.04.008.
7
Psoriasis and Diabetes, a Dangerous Association: Evaluation of Insulin Resistance, Lipid Abnormalities, and Cardiovascular Risk Biomarkers.银屑病与糖尿病:一种危险的关联——胰岛素抵抗、脂质异常及心血管风险生物标志物评估
Front Med (Lausanne). 2021 Mar 23;8:605691. doi: 10.3389/fmed.2021.605691. eCollection 2021.
8
Diabetes-associated dermatological manifestations in primary care and their association with vascular complications.基层医疗中糖尿病相关的皮肤表现及其与血管并发症的关联。
J Diabetes Metab Disord. 2020 Sep 16;19(2):989-996. doi: 10.1007/s40200-020-00594-1. eCollection 2020 Dec.
9
Granuloma annulare: A rare dermatological manifestation of diabetes mellitus.环状肉芽肿:糖尿病一种罕见的皮肤表现。
J Family Med Prim Care. 2019 Oct 31;8(10):3419-3421. doi: 10.4103/jfmpc.jfmpc_616_19. eCollection 2019 Oct.
10
Candida sp. Infections in Patients with Diabetes Mellitus.糖尿病患者的念珠菌属感染
J Clin Med. 2019 Jan 10;8(1):76. doi: 10.3390/jcm8010076.