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抗血管内皮生长因子(VEGF)治疗模拟卵黄样黄斑营养不良的图案性营养不良继发脉络膜新生血管膜的疗效

Efficacy of anti-VEGF in the treatment of choroidal neovascular membrane secondary to pattern dystrophy simulating fundus flavimaculatus.

作者信息

Nangia Purna, Shah Dhaivat, Saurabh Kumar, Roy Rupak

机构信息

Department of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, India.

出版信息

GMS Ophthalmol Cases. 2019 Jun 18;9:Doc21. doi: 10.3205/oc000110. eCollection 2019.

Abstract

Pattern dystrophies are a group of inherited disorders of the retinal pigment epithelium. A 44-year-old female came with loss of vision in her right eye. The fundus of both eyes showed flecks in the posterior pole with a CNVM in the right eye. FFA and SD OCT confirmed the presence of CNVM. The patient underwent treatment with anti-VEGF injection. Post treatment, the vision improved with a reduction in subretinal fluid along with a scarring CNVM. To conclude, we report an extremely rare case of PDSFF associated CNVM and its favourable response to anti-VEGF injection.

摘要

斑纹状营养不良是一组视网膜色素上皮的遗传性疾病。一名44岁女性因右眼视力丧失前来就诊。双眼眼底后极部可见斑点,右眼有脉络膜新生血管(CNVM)。荧光素眼底血管造影(FFA)和频域光学相干断层扫描(SD OCT)证实了CNVM的存在。该患者接受了抗血管内皮生长因子(VEGF)注射治疗。治疗后,视力改善,视网膜下液减少,同时CNVM形成瘢痕。总之,我们报告了一例极其罕见的与图案状黄斑视网膜病变(PDSFF)相关的CNVM病例及其对抗VEGF注射的良好反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8150/6637455/4d8a2e5235bf/OC-09-21-g-001.jpg

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